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Genetic Test For Thiopurine Drug Handling

Nebraska rates for HCPCS 81335

A blood or saliva test that looks for common inherited changes in a gene controlling how the body breaks down a group of medicines used for leukemia, inflammatory bowel disease, and some autoimmune conditions. People carrying these changes clear the drug slowly and can develop dangerously low blood counts on a standard dose. The result is used to set a safe starting dose or to choose a different medicine.

Rates data updated July 2026.

How much does Genetic Test For Thiopurine Drug Handling cost?

$174

Typical negotiated rate. In Nebraska, July 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $115 from a physician practice, and about $347 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$115$115 to $457
FacilityA hospital or hospital-owned outpatient department$347$158 to $457

How much rates vary

Facilitymedian $347 · 10th to 90th $105 to $759Professionalmedian $115 · 10th to 90th $105 to $1,148
$100$200$500$1Kfacility $347professional $115

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$123.03
Median
$457.09
Typical High
$870.96
Aetna
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$114.82
Typical High
$1,148.15
BCBS
Setting
Facility
Modifier
Global
Typical Low
$338.84
Median
$446.68
Typical High
$851.14
BCBS
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$275.42
Typical High
$288.40
Cigna
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$331.13
Typical High
$416.87
Medica
Setting
Facility
Modifier
Global
Typical Low
$104.71
Median
$263.03
Typical High
$831.76
Medica
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$104.71
Typical High
$501.19
Midlands
Setting
Professional
Modifier
Global
Typical Low
$363.08
Median
$363.08
Typical High
$363.08
United
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$165.96
Typical High
$173.78
United
Setting
Professional
Modifier
Global
Typical Low
$100.00
Median
$104.71
Typical High
$478.63

Where Nebraska sits

The same service costs 3.3 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Nebraska· 24th of 51

$174

AK $389DE $117

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.