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Genetic Test For Thiopurine Drug Handling

North Carolina rates for HCPCS 81335

A blood or saliva test that looks for common inherited changes in a gene controlling how the body breaks down a group of medicines used for leukemia, inflammatory bowel disease, and some autoimmune conditions. People carrying these changes clear the drug slowly and can develop dangerously low blood counts on a standard dose. The result is used to set a safe starting dose or to choose a different medicine.

Rates data updated July 2026.

How much does Genetic Test For Thiopurine Drug Handling cost?

$148

Typical negotiated rate. In North Carolina, July 2026.

Insurers have agreed to pay about $148 for this service. The price depends on where it is billed: about $148 from a physician practice, and about $219 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$148$141 to $200
FacilityA hospital or hospital-owned outpatient department$219$155 to $646

How much rates vary

Facilitymedian $219 · 10th to 90th $141 to $708Professionalmedian $148 · 10th to 90th $115 to $263
$100$200$500facility $219professional $148

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$141.25
Median
$302.00
Typical High
$707.95
Aetna
Setting
Professional
Modifier
Global
Typical Low
$117.49
Median
$141.25
Typical High
$229.09
BCBS
Setting
Facility
Modifier
Global
Typical Low
$295.12
Median
$398.11
Typical High
$489.78
BCBS
Setting
Professional
Modifier
Global
Typical Low
$147.91
Median
$173.78
Typical High
$316.23
Cigna
Setting
Facility
Modifier
Global
Typical Low
$131.83
Median
$380.19
Typical High
$794.33
Cigna
Setting
Professional
Modifier
Global
Typical Low
$81.28
Median
$85.11
Typical High
$245.47
Medcost
Setting
Facility
Modifier
Global
Typical Low
$138.04
Median
$158.49
Typical High
$263.03
Medcost
Setting
Professional
Modifier
Global
Typical Low
$154.88
Median
$154.88
Typical High
$154.88
United
Setting
Facility
Modifier
Global
Typical Low
$104.71
Median
$204.17
Typical High
$213.80
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$104.71
Typical High
$186.21
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$831.76
Median
$831.76
Typical High
$831.76
Wellcare
Setting
Professional
Modifier
Global
Typical Low
$870.96
Median
$870.96
Typical High
$1,318.26

Where North Carolina sits

The same service costs 3.3 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 39th of 51

$148

AK $389DE $117

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.