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Genetic Test For Thiopurine Drug Handling

Maine rates for HCPCS 81335

A blood or saliva test that looks for common inherited changes in a gene controlling how the body breaks down a group of medicines used for leukemia, inflammatory bowel disease, and some autoimmune conditions. People carrying these changes clear the drug slowly and can develop dangerously low blood counts on a standard dose. The result is used to set a safe starting dose or to choose a different medicine.

Rates data updated July 2026.

How much does Genetic Test For Thiopurine Drug Handling cost?

$174

Typical negotiated rate. In Maine, July 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $174 from a physician practice, and about $282 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$174$141 to $174
FacilityA hospital or hospital-owned outpatient department$282$174 to $794

How much rates vary

Facilitymedian $282 · 10th to 90th $174 to $1,122Professionalmedian $174 · 10th to 90th $105 to $209
$100$200$500$1Kfacility $282professional $174

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$776.25
Aetna
Setting
Professional
Modifier
Global
Typical Low
$131.83
Median
$141.25
Typical High
$173.78
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$204.17
Median
$1,122.02
Typical High
$1,202.26
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$69.18
Median
$104.71
Typical High
$173.78
Cigna
Setting
Facility
Modifier
Global
Typical Low
$398.11
Median
$398.11
Typical High
$398.11
Cigna
Setting
Professional
Modifier
Global
Typical Low
$112.20
Median
$177.83
Typical High
$218.78
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$208.93
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$776.25
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$173.78
Typical High
$194.98
United
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$173.78
Typical High
$269.15

Where Maine sits

The same service costs 3.3 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maine· 25th of 51

$174

AK $389DE $117

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.