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Genetic Test For Thiopurine Drug Handling

Maryland rates for HCPCS 81335

A blood or saliva test that looks for common inherited changes in a gene controlling how the body breaks down a group of medicines used for leukemia, inflammatory bowel disease, and some autoimmune conditions. People carrying these changes clear the drug slowly and can develop dangerously low blood counts on a standard dose. The result is used to set a safe starting dose or to choose a different medicine.

Rates data updated July 2026.

How much does Genetic Test For Thiopurine Drug Handling cost?

$132

Typical negotiated rate. In Maryland, July 2026.

Insurers have agreed to pay about $132 for this service. Most negotiated rates run $110 to $148.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $83 · 10th to 90th $74 to $83Professionalmedian $132 · 10th to 90th $79 to $182
$100$200$500$1Kfacility $83professional $132

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$83.18
Typical High
$83.18
Aetna
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$141.25
Typical High
$165.96
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$125.89
Median
$125.89
Typical High
$154.88
Cigna
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$107.15
Typical High
$309.03
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$208.93
Typical High
$263.03
United
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$74.13
Typical High
$131.83
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$79.43
Typical High
$154.88
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$87.10
Median
$87.10
Typical High
$87.10

Where Maryland sits

The same service costs 3.3 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 47th of 51

$132

AK $389DE $117

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.