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Genetic Test For Thiopurine Drug Handling

Alabama rates for HCPCS 81335

A blood or saliva test that looks for common inherited changes in a gene controlling how the body breaks down a group of medicines used for leukemia, inflammatory bowel disease, and some autoimmune conditions. People carrying these changes clear the drug slowly and can develop dangerously low blood counts on a standard dose. The result is used to set a safe starting dose or to choose a different medicine.

Rates data updated July 2026.

How much does Genetic Test For Thiopurine Drug Handling cost?

$174

Typical negotiated rate. In Alabama, July 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $135 from a physician practice, and about $200 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$135$105 to $200
FacilityA hospital or hospital-owned outpatient department$200$174 to $209

How much rates vary

Facilitymedian $200 · 10th to 90th $158 to $263Professionalmedian $135 · 10th to 90th $105 to $200
$100$200facility $200professional $135

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$199.53
Typical High
$269.15
Aetna
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$147.91
Typical High
$199.53
BCBS
Setting
Facility
Modifier
Global
Typical Low
$162.18
Median
$194.98
Typical High
$263.03
BCBS
Setting
Professional
Modifier
Global
Typical Low
$89.13
Median
$109.65
Typical High
$169.82
Cigna
Setting
Facility
Modifier
Global
Typical Low
$112.20
Median
$147.91
Typical High
$549.54
Cigna
Setting
Professional
Modifier
Global
Typical Low
$72.44
Median
$79.43
Typical High
$218.78
United
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$158.49
Typical High
$173.78
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$74.13
Typical High
$173.78

Where Alabama sits

The same service costs 3.3 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 21st of 51

$174

AK $389DE $117

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.