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Targeted Single-Gene Variant Test

Ohio rates for HCPCS 81333

A laboratory test that examines one specific gene in a blood or tissue sample and reports whether a defined set of known changes is present. Testing of this kind is ordered when a particular genetic change is suspected, either to confirm a diagnosis or to find out whether someone carries the change.

Rates data updated July 2026.

How much does Targeted Single-Gene Variant Test cost?

$117

Typical negotiated rate. In Ohio, July 2026.

Insurers have agreed to pay about $117 for this service. The price depends on where it is billed: about $110 from a physician practice, and about $191 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$110$72.44 to $132
FacilityA hospital or hospital-owned outpatient department$191$138 to $302

How much rates vary

Facilitymedian $191 · 10th to 90th $112 to $309Professionalmedian $110 · 10th to 90th $55 to $234
$100$200$500facility $191professional $110

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$112.20
Median
$234.42
Typical High
$331.13
Aetna
Setting
Professional
Modifier
Global
Typical Low
$109.65
Median
$112.20
Typical High
$309.03
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$125.89
Median
$144.54
Typical High
$251.19
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$70.79
Typical High
$190.55
CareSource
Setting
Facility
Modifier
Global
Typical Low
$128.82
Median
$128.82
Typical High
$158.49
CareSource
Setting
Professional
Modifier
Global
Typical Low
$186.21
Median
$186.21
Typical High
$186.21
Cigna
Setting
Facility
Modifier
Global
Typical Low
$134.90
Median
$181.97
Typical High
$691.83
Cigna
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$102.33
Typical High
$275.42
Medical Mutual of Ohio
Setting
Facility
Modifier
Global
Typical Low
$147.91
Median
$181.97
Typical High
$758.58
Medical Mutual of Ohio
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$102.33
Typical High
$263.03
Molina
Setting
Professional
Modifier
Global
Typical Low
$93.33
Median
$123.03
Typical High
$147.91
SummaCare
Setting
Professional
Modifier
Global
Typical Low
$117.49
Median
$165.96
Typical High
$316.23
United
Setting
Facility
Modifier
Global
Typical Low
$81.28
Median
$138.04
Typical High
$204.17
United
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$81.28
Typical High
$190.55

Where Ohio sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Ohio· 34th of 51

$117

AK $309DE $91.20

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.