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Targeted Single-Gene Variant Test

New York rates for HCPCS 81333

A laboratory test that examines one specific gene in a blood or tissue sample and reports whether a defined set of known changes is present. Testing of this kind is ordered when a particular genetic change is suspected, either to confirm a diagnosis or to find out whether someone carries the change.

Rates data updated July 2026.

How much does Targeted Single-Gene Variant Test cost?

$138

Typical negotiated rate. In New York, July 2026.

Insurers have agreed to pay about $138 for this service. The price depends on where it is billed: about $112 from a physician practice, and about $224 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$112$74.13 to $166
FacilityA hospital or hospital-owned outpatient department$224$138 to $316

How much rates vary

Facilitymedian $224 · 10th to 90th $112 to $380Professionalmedian $112 · 10th to 90th $55 to $269
$100$200$500$1Kfacility $224professional $112

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$112.20
Median
$234.42
Typical High
$380.19
Aetna
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$112.20
Typical High
$245.47
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$138.04
Median
$138.04
Typical High
$354.81
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$54.95
Typical High
$275.42
CDPHP
Setting
Facility
Modifier
Global
Typical Low
$81.28
Median
$138.04
Typical High
$138.04
CDPHP
Setting
Professional
Modifier
Global
Typical Low
$100.00
Median
$138.04
Typical High
$138.04
Cigna
Setting
Facility
Modifier
Global
Typical Low
$134.90
Median
$295.12
Typical High
$354.81
Cigna
Setting
Professional
Modifier
Global
Typical Low
$83.18
Median
$169.82
Typical High
$501.19
Emblem Health
Setting
Facility
Modifier
Global
Typical Low
$107.15
Median
$173.78
Typical High
$380.19
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$81.28
Median
$114.82
Typical High
$263.03
Excellus BCBS
Setting
Professional
Modifier
Global
Typical Low
$109.65
Median
$134.90
Typical High
$245.47
MVP Health Care
Setting
Facility
Modifier
Global
Typical Low
$13.80
Median
$257.04
Typical High
$50,118.72
MVP Health Care
Setting
Professional
Modifier
Global
Typical Low
$102.33
Median
$138.04
Typical High
$245.47
United
Setting
Facility
Modifier
Global
Typical Low
$123.03
Median
$138.04
Typical High
$204.17
United
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$117.49
Typical High
$309.03
Univera
Setting
Facility
Modifier
Global
Typical Low
$112.20
Median
$144.54
Typical High
$169.82
Univera
Setting
Professional
Modifier
Global
Typical Low
$112.20
Median
$138.04
Typical High
$323.59

Where New York sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

New York· 15th of 51

$138

AK $309DE $91.20

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.