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Targeted Single-Gene Variant Test

Nebraska rates for HCPCS 81333

A laboratory test that examines one specific gene in a blood or tissue sample and reports whether a defined set of known changes is present. Testing of this kind is ordered when a particular genetic change is suspected, either to confirm a diagnosis or to find out whether someone carries the change.

Rates data updated July 2026.

How much does Targeted Single-Gene Variant Test cost?

$129

Typical negotiated rate. In Nebraska, July 2026.

Insurers have agreed to pay about $129 for this service. The price depends on where it is billed: about $91.20 from a physician practice, and about $324 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$91.20$91.20 to $363
FacilityA hospital or hospital-owned outpatient department$324$97.72 to $363

How much rates vary

Facilitymedian $324 · 10th to 90th $81 to $646Professionalmedian $91 · 10th to 90th $81 to $912
$50$100$200$500$1Kfacility $324professional $91

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$97.72
Median
$363.08
Typical High
$676.08
Aetna
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$91.20
Typical High
$912.01
BCBS
Setting
Facility
Modifier
Global
Typical Low
$338.84
Median
$436.52
Typical High
$851.14
BCBS
Setting
Professional
Modifier
Global
Typical Low
$199.53
Median
$213.80
Typical High
$223.87
Cigna
Setting
Professional
Modifier
Global
Typical Low
$165.96
Median
$263.03
Typical High
$331.13
Medica
Setting
Facility
Modifier
Global
Typical Low
$81.28
Median
$173.78
Typical High
$645.65
Medica
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$81.28
Typical High
$398.11
Midlands
Setting
Professional
Modifier
Global
Typical Low
$281.84
Median
$281.84
Typical High
$281.84
United
Setting
Facility
Modifier
Global
Typical Low
$57.54
Median
$128.82
Typical High
$138.04
United
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$81.28
Typical High
$380.19

Where Nebraska sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Nebraska· 29th of 51

$129

AK $309DE $91.20

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.