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Targeted Single-Gene Variant Test

Michigan rates for HCPCS 81333

A laboratory test that examines one specific gene in a blood or tissue sample and reports whether a defined set of known changes is present. Testing of this kind is ordered when a particular genetic change is suspected, either to confirm a diagnosis or to find out whether someone carries the change.

Rates data updated July 2026.

How much does Targeted Single-Gene Variant Test cost?

$129

Typical negotiated rate. In Michigan, July 2026.

Insurers have agreed to pay about $129 for this service. The price depends on where it is billed: about $112 from a physician practice, and about $129 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$112$95.50 to $129
FacilityA hospital or hospital-owned outpatient department$129$129 to $162

How much rates vary

Facilitymedian $129 · 10th to 90th $129 to $240Professionalmedian $112 · 10th to 90th $74 to $162
$100$200facility $129professional $112

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$128.82
Median
$128.82
Typical High
$239.88
Aetna
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$128.82
Typical High
$162.18
BCBS
Setting
Facility
Modifier
Global
Typical Low
$95.50
Median
$95.50
Typical High
$95.50
BCBS
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$95.50
Typical High
$95.50
Cigna
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$117.49
Typical High
$208.93
Health Alliance Plan
Setting
Facility
Modifier
Global
Typical Low
$128.82
Median
$141.25
Typical High
$331.13
Health Alliance Plan
Setting
Professional
Modifier
Global
Typical Low
$109.65
Median
$138.04
Typical High
$186.21
Priority Health
Setting
Professional
Modifier
Global
Typical Low
$138.04
Median
$165.96
Typical High
$309.03
United
Setting
Facility
Modifier
Global
Typical Low
$81.28
Median
$138.04
Typical High
$165.96
United
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$81.28
Typical High
$138.04

Where Michigan sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 28th of 51

$129

AK $309DE $91.20

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.