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Targeted Single-Gene Variant Test

Indiana rates for HCPCS 81333

A laboratory test that examines one specific gene in a blood or tissue sample and reports whether a defined set of known changes is present. Testing of this kind is ordered when a particular genetic change is suspected, either to confirm a diagnosis or to find out whether someone carries the change.

Rates data updated July 2026.

How much does Targeted Single-Gene Variant Test cost?

$112

Typical negotiated rate. In Indiana, July 2026.

Insurers have agreed to pay about $112 for this service. The price depends on where it is billed: about $112 from a physician practice, and about $138 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$112$81.28 to $112
FacilityA hospital or hospital-owned outpatient department$138$138 to $275

How much rates vary

Facilitymedian $138 · 10th to 90th $138 to $407Professionalmedian $112 · 10th to 90th $55 to $123
$100$200$500$1Kfacility $138professional $112

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$112.20
Median
$151.36
Typical High
$407.38
Aetna
Setting
Professional
Modifier
Global
Typical Low
$107.15
Median
$112.20
Typical High
$123.03
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$138.04
Median
$138.04
Typical High
$407.38
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$54.95
Typical High
$109.65
CareSource
Setting
Facility
Modifier
Global
Typical Low
$131.83
Median
$131.83
Typical High
$131.83
Cigna
Setting
Facility
Modifier
Global
Typical Low
$138.04
Median
$138.04
Typical High
$257.04
Cigna
Setting
Professional
Modifier
Global
Typical Low
$60.26
Median
$123.03
Typical High
$194.98
United
Setting
Facility
Modifier
Global
Typical Low
$138.04
Median
$138.04
Typical High
$158.49
United
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$81.28
Typical High
$165.96

Where Indiana sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 39th of 51

$112

AK $309DE $91.20

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.