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Alpha-1 Antitrypsin Gene Test

South Dakota rates for HCPCS 81332

This service is a genetic laboratory test that looks for common gene changes linked to alpha-1 antitrypsin deficiency, an inherited condition that can cause lung and liver disease. It is used to help confirm the diagnosis in people with unexplained liver disease, early emphysema, or a family history of the condition. The test is run on a blood sample.

Rates data updated July 2026.

How much does Alpha-1 Antitrypsin Gene Test cost?

$83.18

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $83.18 for this service. The price depends on where it is billed: about $70.79 from a physician practice, and about $83.18 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$70.79$33.88 to $105
FacilityA hospital or hospital-owned outpatient department$83.18$79.43 to $83.18

How much rates vary

Facilitymedian $83 · 10th to 90th $49 to $83Professionalmedian $71 · 10th to 90th $30 to $117
$20$50$100facility $83professional $71

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$30.90
Median
$50.12
Typical High
$50.12
Aetna
Setting
Professional
Modifier
Global
Typical Low
$29.51
Median
$33.88
Typical High
$40.74
Cigna
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$83.18
Typical High
$83.18
Cigna
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$83.18
Typical High
$104.71
Medica
Setting
Facility
Modifier
Global
Typical Low
$40.74
Median
$48.98
Typical High
$165.96
Medica
Setting
Professional
Modifier
Global
Typical Low
$26.30
Median
$30.20
Typical High
$218.78
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$104.71
Typical High
$120.23
United
Setting
Professional
Modifier
Global
Typical Low
$18.20
Median
$30.20
Typical High
$58.88
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$43.65
Median
$43.65
Typical High
$43.65

Where South Dakota sits

The same service costs 3.2 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 3rd of 51

$83.18

NE $105DC $33.11

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.