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Alpha-1 Antitrypsin Gene Test

Massachusetts rates for HCPCS 81332

This service is a genetic laboratory test that looks for common gene changes linked to alpha-1 antitrypsin deficiency, an inherited condition that can cause lung and liver disease. It is used to help confirm the diagnosis in people with unexplained liver disease, early emphysema, or a family history of the condition. The test is run on a blood sample.

Rates data updated July 2026.

How much does Alpha-1 Antitrypsin Gene Test cost?

$43.65

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $43.65 for this service. The price depends on where it is billed: about $43.65 from a physician practice, and about $107 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$43.65$43.65 to $66.07
FacilityA hospital or hospital-owned outpatient department$107$61.66 to $132

How much rates vary

Facilitymedian $107 · 10th to 90th $42 to $158Professionalmedian $44 · 10th to 90th $34 to $110
$50$100$200$500$1K$2Kfacility $107professional $44

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$41.69
Median
$100.00
Typical High
$186.21
Aetna
Setting
Professional
Modifier
Global
Typical Low
$32.36
Median
$41.69
Typical High
$131.83
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$39.81
Median
$61.66
Typical High
$151.36
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$26.30
Median
$44.67
Typical High
$144.54
BCBS
Setting
Facility
Modifier
Global
Typical Low
$85.11
Median
$107.15
Typical High
$154.88
BCBS
Setting
Professional
Modifier
Global
Typical Low
$42.66
Median
$56.23
Typical High
$56.23
Cigna
Setting
Facility
Modifier
Global
Typical Low
$33.88
Median
$60.26
Typical High
$91.20
Cigna
Setting
Professional
Modifier
Global
Typical Low
$26.30
Median
$45.71
Typical High
$114.82
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$3,630.78
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$32.36
Median
$63.10
Typical High
$74.13
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$43.65
Median
$43.65
Typical High
$83.18
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$39.81
Median
$61.66
Typical High
$151.36
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$26.30
Median
$44.67
Typical High
$144.54
United
Setting
Facility
Modifier
Global
Typical Low
$35.48
Median
$43.65
Typical High
$70.79
United
Setting
Professional
Modifier
Global
Typical Low
$26.30
Median
$43.65
Typical High
$104.71

Where Massachusetts sits

The same service costs 3.2 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 31st of 51

$43.65

NE $105DC $33.11

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.