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Prader-Willi/Angelman Genetic Test

South Dakota rates for HCPCS 81331

This service is a genetic laboratory test that looks at a specific pattern of gene activity to help diagnose Prader-Willi syndrome or Angelman syndrome, two different inherited conditions that affect development. It is typically ordered when a child shows developmental delay, low muscle tone, feeding difficulties, or other features suggestive of one of these conditions. The test is run on a blood sample.

Rates data updated July 2026.

How much does Prader-Willi/Angelman Genetic Test cost?

$75.86

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $75.86 for this service. The price depends on where it is billed: about $67.61 from a physician practice, and about $97.72 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$67.61$39.81 to $105
FacilityA hospital or hospital-owned outpatient department$97.72$97.72 to $97.72

How much rates vary

Facilitymedian $98 · 10th to 90th $58 to $98Professionalmedian $68 · 10th to 90th $34 to $123
$20.0$50.0$100.0$200.0facility $98professional $68

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$35.48
Median
$57.54
Typical High
$57.54
Aetna
Setting
Professional
Modifier
Global
Typical Low
$33.88
Median
$39.81
Typical High
$58.88
Cigna
Setting
Facility
Modifier
Global
Typical Low
$97.72
Median
$97.72
Typical High
$97.72
Cigna
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$97.72
Typical High
$123.03
Medica
Setting
Facility
Modifier
Global
Typical Low
$47.86
Median
$57.54
Typical High
$234.42
Medica
Setting
Professional
Modifier
Global
Typical Low
$26.30
Median
$26.30
Typical High
$263.03
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$72.44
Median
$120.23
Typical High
$141.25
United
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$30.90
Typical High
$67.61
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$51.29
Typical High
$51.29

Where South Dakota sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

South Dakota $75.86 · 4th of 51
AK $115MD $38.02

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.