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Prader-Willi/Angelman Genetic Test

South Dakota rates for HCPCS 81331

This service is a genetic laboratory test that looks at a specific pattern of gene activity to help diagnose Prader-Willi syndrome or Angelman syndrome, two different inherited conditions that affect development. It is typically ordered when a child shows developmental delay, low muscle tone, feeding difficulties, or other features suggestive of one of these conditions. The test is run on a blood sample.

Rates data updated October 2026.

How much does Prader-Willi/Angelman Genetic Test cost?

$57.54

Typical negotiated rate. In South Dakota, October 2026.

Insurers have agreed to pay about $57.54 for this service. The price depends on where it is billed: about $58.88 from a physician practice, and about $57.54 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$58.88$45.71 to $97.72
FacilityA hospital or hospital-owned outpatient department$57.54$57.54 to $97.72

How much rates vary

Facilitymedian $58 · 10th to 90th $48 to $98Professionalmedian $59 · 10th to 90th $26 to $123
$20$50$100$200facility $58professional $59

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$35.48
Median
$35.48
Typical High
$57.54
Aetna
Setting
Professional
Modifier
None
Typical Low
$33.88
Median
$33.88
Typical High
$58.88
Cigna
Setting
Facility
Modifier
None
Typical Low
$97.72
Median
$97.72
Typical High
$97.72
Cigna
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$97.72
Typical High
$123.03
Medica
Setting
Facility
Modifier
None
Typical Low
$48.98
Median
$57.54
Typical High
$93.33
Medica
Setting
Professional
Modifier
None
Typical Low
$26.30
Median
$45.71
Typical High
$93.33
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$75.86
Median
$120.23
Typical High
$141.25
United
Setting
Professional
Modifier
None
Typical Low
$21.38
Median
$30.90
Typical High
$51.29
Wellmark
Setting
Professional
Modifier
None
Typical Low
$51.29
Median
$51.29
Typical High
$51.29

Where South Dakota sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 17th of 51

$57.54

AK $115NE $33.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.