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Prader-Willi/Angelman Genetic Test

South Carolina rates for HCPCS 81331

This service is a genetic laboratory test that looks at a specific pattern of gene activity to help diagnose Prader-Willi syndrome or Angelman syndrome, two different inherited conditions that affect development. It is typically ordered when a child shows developmental delay, low muscle tone, feeding difficulties, or other features suggestive of one of these conditions. The test is run on a blood sample.

Rates data updated July 2026.

Facilitymedian $95 · 10th–90th $40$2400%10%10th90th$95Professionalmedian $40 · 10th–90th $33$620%50%10th90th$40$10.0$20.0$50.0$100.0$200.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$35.48
Median
$125.89
Typical High
$239.88
Aetna
Setting
Professional
Modifier
Global
Typical Low
$39.81
Median
$39.81
Typical High
$45.71
BCBS
Setting
Facility
Modifier
Global
Typical Low
$316.23
Median
$316.23
Typical High
$338.84
BCBS
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$64.57
Typical High
$109.65
Cigna
Setting
Facility
Modifier
Global
Typical Low
$95.50
Median
$151.36
Typical High
$288.40
Cigna
Setting
Professional
Modifier
Global
Typical Low
$22.91
Median
$28.18
Typical High
$61.66
Medcost
Setting
Facility
Modifier
Global
Typical Low
$39.81
Median
$48.98
Typical High
$70.79
United
Setting
Facility
Modifier
Global
Typical Low
$45.71
Median
$51.29
Typical High
$61.66
United
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$30.90
Typical High
$51.29