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Prader-Willi/Angelman Genetic Test

Pennsylvania rates for HCPCS 81331

This service is a genetic laboratory test that looks at a specific pattern of gene activity to help diagnose Prader-Willi syndrome or Angelman syndrome, two different inherited conditions that affect development. It is typically ordered when a child shows developmental delay, low muscle tone, feeding difficulties, or other features suggestive of one of these conditions. The test is run on a blood sample.

Rates data updated October 2026.

How much does Prader-Willi/Angelman Genetic Test cost?

$43.65

Typical negotiated rate. In Pennsylvania, October 2026.

Insurers have agreed to pay about $43.65 for this service. The price depends on where it is billed: about $41.69 from a physician practice, and about $69.18 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$41.69$39.81 to $51.29
FacilityA hospital or hospital-owned outpatient department$69.18$51.29 to $148

How much rates vary

Facilitymedian $69 · 10th to 90th $42 to $257Professionalmedian $42 · 10th to 90th $31 to $76
$20$100$500$2Kfacility $69professional $42

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$41.69
Median
$43.65
Typical High
$147.91
Aetna
Setting
Professional
Modifier
None
Typical Low
$41.69
Median
$41.69
Typical High
$58.88
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$20.89
Median
$20.89
Typical High
$23.99
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$8.32
Median
$8.32
Typical High
$9.55
Capital Blue Cross
Setting
Facility
Modifier
None
Typical Low
$199.53
Median
$257.04
Typical High
$5,011.87
Capital Blue Cross
Setting
Professional
Modifier
None
Typical Low
$36.31
Median
$39.81
Typical High
$123.03
Cigna
Setting
Facility
Modifier
None
Typical Low
$50.12
Median
$83.18
Typical High
$154.88
Cigna
Setting
Professional
Modifier
None
Typical Low
$27.54
Median
$54.95
Typical High
$79.43
Emblem Health
Setting
Professional
Modifier
None
Typical Low
$35.48
Median
$67.61
Typical High
$67.61
Geisinger
Setting
Facility
Modifier
None
Typical Low
$51.29
Median
$51.29
Typical High
$51.29
Geisinger
Setting
Professional
Modifier
None
Typical Low
$54.95
Median
$81.28
Typical High
$134.90
Highmark BCBS
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$123.03
Typical High
$933.25
Martin's Point
Setting
Facility
Modifier
None
Typical Low
$41.69
Median
$41.69
Typical High
$147.91
Martin's Point
Setting
Professional
Modifier
None
Typical Low
$41.69
Median
$41.69
Typical High
$58.88
Martin's Point
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$20.89
Median
$20.89
Typical High
$21.88
Martin's Point
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$8.32
Median
$8.32
Typical High
$8.71
UPMC Health Plan
Setting
Facility
Modifier
None
Typical Low
$51.29
Median
$66.07
Typical High
$125.89
UPMC Health Plan
Setting
Professional
Modifier
None
Typical Low
$51.29
Median
$66.07
Typical High
$66.07
United
Setting
Facility
Modifier
None
Typical Low
$45.71
Median
$51.29
Typical High
$61.66
United
Setting
Professional
Modifier
None
Typical Low
$21.38
Median
$30.90
Typical High
$61.66

Where Pennsylvania sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 36th of 51

$43.65

AK $115NE $33.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.