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Prader-Willi/Angelman Genetic Test

Pennsylvania rates for HCPCS 81331

This service is a genetic laboratory test that looks at a specific pattern of gene activity to help diagnose Prader-Willi syndrome or Angelman syndrome, two different inherited conditions that affect development. It is typically ordered when a child shows developmental delay, low muscle tone, feeding difficulties, or other features suggestive of one of these conditions. The test is run on a blood sample.

Rates data updated July 2026.

How much does Prader-Willi/Angelman Genetic Test cost?

$58.88

Typical negotiated rate. In Pennsylvania, July 2026.

Insurers have agreed to pay about $58.88 for this service. The price depends on where it is billed: about $47.86 from a physician practice, and about $107 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$47.86$41.69 to $58.88
FacilityA hospital or hospital-owned outpatient department$107$61.66 to $129

How much rates vary

Facilitymedian $107 · 10th to 90th $44 to $191Professionalmedian $48 · 10th to 90th $40 to $117
$100.0$1.0K$10.0Kfacility $107professional $48

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$43.65
Median
$120.23
Typical High
$181.97
Aetna
Setting
Professional
Modifier
Global
Typical Low
$41.69
Median
$47.86
Typical High
$151.36
Capital Blue Cross
Setting
Facility
Modifier
Global
Typical Low
$186.21
Median
$251.19
Typical High
$8,511.38
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$39.81
Median
$39.81
Typical High
$39.81
Cigna
Setting
Facility
Modifier
Global
Typical Low
$50.12
Median
$83.18
Typical High
$173.78
Cigna
Setting
Professional
Modifier
Global
Typical Low
$26.92
Median
$54.95
Typical High
$114.82
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$35.48
Median
$35.48
Typical High
$67.61
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$51.29
Median
$51.29
Typical High
$51.29
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$85.11
Typical High
$134.90
Highmark BCBS
Setting
Facility
Modifier
Global
Typical Low
$123.03
Median
$123.03
Typical High
$933.25
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$41.69
Median
$120.23
Typical High
$173.78
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$41.69
Median
$48.98
Typical High
$181.97
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$51.29
Median
$102.33
Typical High
$107.15
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$51.29
Typical High
$52.48
United
Setting
Facility
Modifier
Global
Typical Low
$45.71
Median
$51.29
Typical High
$61.66
United
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$30.90
Typical High
$75.86

Where Pennsylvania sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Pennsylvania $58.88 · 12th of 51
AK $115MD $38.02

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.