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Prader-Willi/Angelman Genetic Test

Ohio rates for HCPCS 81331

This service is a genetic laboratory test that looks at a specific pattern of gene activity to help diagnose Prader-Willi syndrome or Angelman syndrome, two different inherited conditions that affect development. It is typically ordered when a child shows developmental delay, low muscle tone, feeding difficulties, or other features suggestive of one of these conditions. The test is run on a blood sample.

Rates data updated October 2026.

How much does Prader-Willi/Angelman Genetic Test cost?

$40.74

Typical negotiated rate. In Ohio, October 2026.

Insurers have agreed to pay about $40.74 for this service. The price depends on where it is billed: about $27.54 from a physician practice, and about $70.79 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$27.54$20.42 to $47.86
FacilityA hospital or hospital-owned outpatient department$70.79$53.70 to $95.50

How much rates vary

Facilitymedian $71 · 10th to 90th $47 to $138Professionalmedian $28 · 10th to 90th $20 to $87
$20$50$100$200$500facility $71professional $28

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$52.48
Median
$112.20
Typical High
$169.82
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$23.99
Median
$47.86
Typical High
$64.57
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$9.55
Median
$19.05
Typical High
$25.70
Aetna
Setting
Professional
Modifier
None
Typical Low
$40.74
Median
$40.74
Typical High
$478.63
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$20.42
Median
$20.42
Typical High
$239.88
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$8.13
Median
$8.13
Typical High
$95.50
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$41.69
Median
$58.88
Typical High
$93.33
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$20.42
Median
$20.42
Typical High
$69.18
CareSource
Setting
Professional
Modifier
None
Typical Low
$69.18
Median
$69.18
Typical High
$69.18
Cigna
Setting
Facility
Modifier
None
Typical Low
$50.12
Median
$61.66
Typical High
$208.93
Cigna
Setting
Professional
Modifier
None
Typical Low
$23.44
Median
$23.44
Typical High
$91.20
Medical Mutual of Ohio
Setting
Facility
Modifier
None
Typical Low
$54.95
Median
$67.61
Typical High
$208.93
Medical Mutual of Ohio
Setting
Professional
Modifier
None
Typical Low
$23.44
Median
$23.44
Typical High
$91.20
Molina
Setting
Professional
Modifier
None
Typical Low
$34.67
Median
$45.71
Typical High
$63.10
SummaCare
Setting
Professional
Modifier
None
Typical Low
$43.65
Median
$63.10
Typical High
$81.28
United
Setting
Facility
Modifier
None
Typical Low
$18.20
Median
$45.71
Typical High
$75.86
United
Setting
Professional
Modifier
None
Typical Low
$21.38
Median
$30.90
Typical High
$72.44

Where Ohio sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Ohio· 46th of 51

$40.74

AK $115NE $33.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.