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Prader-Willi/Angelman Genetic Test

North Carolina rates for HCPCS 81331

This service is a genetic laboratory test that looks at a specific pattern of gene activity to help diagnose Prader-Willi syndrome or Angelman syndrome, two different inherited conditions that affect development. It is typically ordered when a child shows developmental delay, low muscle tone, feeding difficulties, or other features suggestive of one of these conditions. The test is run on a blood sample.

Rates data updated July 2026.

How much does Prader-Willi/Angelman Genetic Test cost?

$43.65

Typical negotiated rate. In North Carolina, July 2026.

Insurers have agreed to pay about $43.65 for this service. The price depends on where it is billed: about $40.74 from a physician practice, and about $67.61 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$40.74$40.74 to $61.66
FacilityA hospital or hospital-owned outpatient department$67.61$44.67 to $162

How much rates vary

Facilitymedian $68 · 10th to 90th $41 to $501Professionalmedian $41 · 10th to 90th $26 to $76
$10.0$20.0$50.0$100.0$200.0$500.0facility $68professional $41

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$40.74
Median
$112.20
Typical High
$501.19
Aetna
Setting
Professional
Modifier
Global
Typical Low
$37.15
Median
$40.74
Typical High
$75.86
BCBS
Setting
Facility
Modifier
Global
Typical Low
$87.10
Median
$114.82
Typical High
$128.82
BCBS
Setting
Professional
Modifier
Global
Typical Low
$22.91
Median
$45.71
Typical High
$81.28
Cigna
Setting
Facility
Modifier
Global
Typical Low
$38.90
Median
$112.20
Typical High
$234.42
Cigna
Setting
Professional
Modifier
Global
Typical Low
$23.44
Median
$23.99
Typical High
$69.18
Medcost
Setting
Facility
Modifier
Global
Typical Low
$40.74
Median
$53.70
Typical High
$79.43
Medcost
Setting
Professional
Modifier
Global
Typical Low
$87.10
Median
$87.10
Typical High
$87.10
United
Setting
Facility
Modifier
Global
Typical Low
$30.90
Median
$60.26
Typical High
$61.66
United
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$30.90
Typical High
$53.70
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$239.88
Median
$239.88
Typical High
$239.88
Wellcare
Setting
Professional
Modifier
Global
Typical Low
$263.03
Median
$263.03
Typical High
$380.19

Where North Carolina sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

North Carolina $43.65 · 42nd of 51
AK $115MD $38.02

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.