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Prader-Willi/Angelman Genetic Test

Missouri rates for HCPCS 81331

This service is a genetic laboratory test that looks at a specific pattern of gene activity to help diagnose Prader-Willi syndrome or Angelman syndrome, two different inherited conditions that affect development. It is typically ordered when a child shows developmental delay, low muscle tone, feeding difficulties, or other features suggestive of one of these conditions. The test is run on a blood sample.

Rates data updated July 2026.

How much does Prader-Willi/Angelman Genetic Test cost?

$51.29

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $51.29 for this service. The price depends on where it is billed: about $44.67 from a physician practice, and about $66.07 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$44.67$30.90 to $61.66
FacilityA hospital or hospital-owned outpatient department$66.07$51.29 to $89.13

How much rates vary

Facilitymedian $66 · 10th to 90th $49 to $117Professionalmedian $45 · 10th to 90th $20 to $100
$10.0$20.0$50.0$100.0$200.0facility $66professional $45

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$48.98
Median
$85.11
Typical High
$117.49
Aetna
Setting
Professional
Modifier
Global
Typical Low
$43.65
Median
$48.98
Typical High
$104.71
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$51.29
Median
$51.29
Typical High
$177.83
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$18.20
Median
$31.62
Typical High
$89.13
BCBS
Setting
Facility
Modifier
Global
Typical Low
$70.79
Median
$75.86
Typical High
$131.83
BCBS
Setting
Professional
Modifier
Global
Typical Low
$35.48
Median
$51.29
Typical High
$57.54
Cigna
Setting
Facility
Modifier
Global
Typical Low
$61.66
Median
$100.00
Typical High
$251.19
Cigna
Setting
Professional
Modifier
Global
Typical Low
$23.44
Median
$39.81
Typical High
$74.13
Medica
Setting
Facility
Modifier
Global
Typical Low
$44.67
Median
$61.66
Typical High
$239.88
Medica
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$30.90
Typical High
$263.03
United
Setting
Facility
Modifier
Global
Typical Low
$21.38
Median
$51.29
Typical High
$61.66
United
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$30.90
Typical High
$69.18

Where Missouri sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Missouri $51.29 · 30th of 51
AK $115MD $38.02

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.