go back

Prader-Willi/Angelman Genetic Test

Missouri rates for HCPCS 81331

This service is a genetic laboratory test that looks at a specific pattern of gene activity to help diagnose Prader-Willi syndrome or Angelman syndrome, two different inherited conditions that affect development. It is typically ordered when a child shows developmental delay, low muscle tone, feeding difficulties, or other features suggestive of one of these conditions. The test is run on a blood sample.

Rates data updated October 2026.

How much does Prader-Willi/Angelman Genetic Test cost?

$48.98

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $48.98 for this service. The price depends on where it is billed: about $43.65 from a physician practice, and about $89.13 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$43.65$30.90 to $81.28
FacilityA hospital or hospital-owned outpatient department$89.13$61.66 to $155

How much rates vary

Facilitymedian $89 · 10th to 90th $50 to $240Professionalmedian $44 · 10th to 90th $25 to $129
$20$50$100$200facility $89professional $44

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$43.65
Median
$66.07
Typical High
$93.33
Aetna
Setting
Professional
Modifier
None
Typical Low
$43.65
Median
$48.98
Typical High
$58.88
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$51.29
Median
$51.29
Typical High
$234.42
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$30.90
Median
$46.77
Typical High
$91.20
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$70.79
Median
$79.43
Typical High
$138.04
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$35.48
Median
$51.29
Typical High
$97.72
Cigna
Setting
Facility
Modifier
None
Typical Low
$61.66
Median
$114.82
Typical High
$251.19
Cigna
Setting
Professional
Modifier
None
Typical Low
$23.99
Median
$48.98
Typical High
$66.07
Medica
Setting
Facility
Modifier
None
Typical Low
$45.71
Median
$89.13
Typical High
$239.88
Medica
Setting
Professional
Modifier
None
Typical Low
$25.70
Median
$52.48
Typical High
$263.03
United
Setting
Facility
Modifier
None
Typical Low
$45.71
Median
$45.71
Typical High
$45.71
United
Setting
Professional
Modifier
None
Typical Low
$21.38
Median
$30.90
Typical High
$69.18
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$21.88
Median
$21.88
Typical High
$29.51
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$8.71
Median
$8.71
Typical High
$11.75

Where Missouri sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 34th of 51

$48.98

AK $115NE $33.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.