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Prader-Willi/Angelman Genetic Test

Massachusetts rates for HCPCS 81331

This service is a genetic laboratory test that looks at a specific pattern of gene activity to help diagnose Prader-Willi syndrome or Angelman syndrome, two different inherited conditions that affect development. It is typically ordered when a child shows developmental delay, low muscle tone, feeding difficulties, or other features suggestive of one of these conditions. The test is run on a blood sample.

Rates data updated July 2026.

How much does Prader-Willi/Angelman Genetic Test cost?

$53.70

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $53.70 for this service. The price depends on where it is billed: about $51.29 from a physician practice, and about $102 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$51.29$51.29 to $58.88
FacilityA hospital or hospital-owned outpatient department$102$81.28 to $148

How much rates vary

Facilitymedian $102 · 10th to 90th $56 to $166Professionalmedian $51 · 10th to 90th $42 to $123
$100.0$1.0K$10.0Kfacility $102professional $51

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$51.29
Median
$95.50
Typical High
$151.36
Aetna
Setting
Professional
Modifier
Global
Typical Low
$58.88
Median
$58.88
Typical High
$154.88
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$158.49
Typical High
$239.88
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$30.90
Median
$51.29
Typical High
$151.36
BCBS
Setting
Facility
Modifier
Global
Typical Low
$81.28
Median
$102.33
Typical High
$147.91
BCBS
Setting
Professional
Modifier
Global
Typical Low
$26.30
Median
$26.30
Typical High
$26.30
Cigna
Setting
Facility
Modifier
Global
Typical Low
$33.11
Median
$70.79
Typical High
$107.15
Cigna
Setting
Professional
Modifier
Global
Typical Low
$30.90
Median
$54.95
Typical High
$134.90
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$3,630.78
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$38.02
Median
$74.13
Typical High
$87.10
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$51.29
Typical High
$85.11
Health New England
Setting
Facility
Modifier
Global
Typical Low
$269.15
Median
$269.15
Typical High
$269.15
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$158.49
Typical High
$239.88
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$30.90
Median
$51.29
Typical High
$151.36
United
Setting
Facility
Modifier
Global
Typical Low
$30.90
Median
$51.29
Typical High
$61.66
United
Setting
Professional
Modifier
Global
Typical Low
$30.90
Median
$51.29
Typical High
$102.33

Where Massachusetts sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Massachusetts $53.70 · 26th of 51
AK $115MD $38.02

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.