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Prader-Willi/Angelman Genetic Test

Kentucky rates for HCPCS 81331

This service is a genetic laboratory test that looks at a specific pattern of gene activity to help diagnose Prader-Willi syndrome or Angelman syndrome, two different inherited conditions that affect development. It is typically ordered when a child shows developmental delay, low muscle tone, feeding difficulties, or other features suggestive of one of these conditions. The test is run on a blood sample.

Rates data updated October 2026.

How much does Prader-Willi/Angelman Genetic Test cost?

$40.74

Typical negotiated rate. In Kentucky, October 2026.

Insurers have agreed to pay about $40.74 for this service. The price depends on where it is billed: about $40.74 from a physician practice, and about $51.29 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$40.74$30.90 to $51.29
FacilityA hospital or hospital-owned outpatient department$51.29$42.66 to $58.88

How much rates vary

Facilitymedian $51 · 10th to 90th $40 to $100Professionalmedian $41 · 10th to 90th $26 to $245
$20$50$100$200facility $51professional $41

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$41.69
Median
$42.66
Typical High
$58.88
Aetna
Setting
Professional
Modifier
None
Typical Low
$38.02
Median
$41.69
Typical High
$58.88
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$31.62
Median
$51.29
Typical High
$53.70
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$24.55
Median
$40.74
Typical High
$51.29
CareSource
Setting
Facility
Modifier
None
Typical Low
$51.29
Median
$61.66
Typical High
$70.79
CareSource
Setting
Professional
Modifier
None
Typical Low
$54.95
Median
$66.07
Typical High
$85.11
Cigna
Setting
Facility
Modifier
None
Typical Low
$39.81
Median
$100.00
Typical High
$120.23
Cigna
Setting
Professional
Modifier
None
Typical Low
$38.02
Median
$245.47
Typical High
$245.47
United
Setting
Professional
Modifier
None
Typical Low
$21.88
Median
$30.90
Typical High
$81.28
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$19.05
Median
$20.89
Typical High
$29.51
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$7.59
Median
$8.32
Typical High
$11.75

Where Kentucky sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Kentucky· 45th of 51

$40.74

AK $115NE $33.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.