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Prader-Willi/Angelman Genetic Test

Indiana rates for HCPCS 81331

This service is a genetic laboratory test that looks at a specific pattern of gene activity to help diagnose Prader-Willi syndrome or Angelman syndrome, two different inherited conditions that affect development. It is typically ordered when a child shows developmental delay, low muscle tone, feeding difficulties, or other features suggestive of one of these conditions. The test is run on a blood sample.

Rates data updated October 2026.

How much does Prader-Willi/Angelman Genetic Test cost?

$40.74

Typical negotiated rate. In Indiana, October 2026.

Insurers have agreed to pay about $40.74 for this service. The price depends on where it is billed: about $30.90 from a physician practice, and about $51.29 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$30.90$20.42 to $47.86
FacilityA hospital or hospital-owned outpatient department$51.29$45.71 to $102

How much rates vary

Facilitymedian $51 · 10th to 90th $41 to $155Professionalmedian $31 · 10th to 90th $20 to $76
$20$50$100$200$500$1K$2Kfacility $51professional $31

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$41.69
Median
$75.86
Typical High
$190.55
Aetna
Setting
Professional
Modifier
None
Typical Low
$38.02
Median
$41.69
Typical High
$75.86
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$19.95
Median
$20.89
Typical High
$38.02
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$8.13
Median
$8.32
Typical High
$15.49
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$40.74
Median
$51.29
Typical High
$154.88
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$20.42
Median
$20.42
Typical High
$75.86
Cigna
Setting
Facility
Modifier
None
Typical Low
$36.31
Median
$51.29
Typical High
$144.54
Cigna
Setting
Professional
Modifier
None
Typical Low
$23.99
Median
$45.71
Typical High
$97.72
Physicians Health Plan of Northern Indiana
Setting
Facility
Modifier
None
Typical Low
$85.11
Median
$128.82
Typical High
$2,187.76
Physicians Health Plan of Northern Indiana
Setting
Professional
Modifier
None
Typical Low
$37.15
Median
$43.65
Typical High
$77.62
United
Setting
Professional
Modifier
None
Typical Low
$21.38
Median
$30.90
Typical High
$61.66

Where Indiana sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 43rd of 51

$40.74

AK $115NE $33.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.