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Prader-Willi/Angelman Genetic Test

Illinois rates for HCPCS 81331

This service is a genetic laboratory test that looks at a specific pattern of gene activity to help diagnose Prader-Willi syndrome or Angelman syndrome, two different inherited conditions that affect development. It is typically ordered when a child shows developmental delay, low muscle tone, feeding difficulties, or other features suggestive of one of these conditions. The test is run on a blood sample.

Rates data updated July 2026.

How much does Prader-Willi/Angelman Genetic Test cost?

$47.86

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $47.86 for this service. The price depends on where it is billed: about $41.69 from a physician practice, and about $79.43 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$41.69$38.90 to $58.88
FacilityA hospital or hospital-owned outpatient department$79.43$52.48 to $102

How much rates vary

Facilitymedian $79 · 10th to 90th $44 to $141Professionalmedian $42 · 10th to 90th $3 to $95
$5.0$20.0$100.0$500.0$2.0Kfacility $79professional $42

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$41.69
Median
$79.43
Typical High
$104.71
Aetna
Setting
Professional
Modifier
Global
Typical Low
$40.74
Median
$43.65
Typical High
$95.50
BCBS
Setting
Facility
Modifier
Global
Typical Low
$63.10
Median
$177.83
Typical High
$645.65
BCBS
Setting
Professional
Modifier
Global
Typical Low
$3.47
Median
$35.48
Typical High
$38.90
Cigna
Setting
Facility
Modifier
Global
Typical Low
$72.44
Median
$107.15
Typical High
$234.42
Cigna
Setting
Professional
Modifier
Global
Typical Low
$25.12
Median
$61.66
Typical High
$87.10
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$128.82
Typical High
$660.69
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$66.07
Typical High
$66.07
United
Setting
Facility
Modifier
Global
Typical Low
$51.29
Median
$51.29
Typical High
$102.33
United
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$30.90
Typical High
$51.29

Where Illinois sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Illinois $47.86 · 39th of 51
AK $115MD $38.02

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.