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Prader-Willi/Angelman Genetic Test

Illinois rates for HCPCS 81331

This service is a genetic laboratory test that looks at a specific pattern of gene activity to help diagnose Prader-Willi syndrome or Angelman syndrome, two different inherited conditions that affect development. It is typically ordered when a child shows developmental delay, low muscle tone, feeding difficulties, or other features suggestive of one of these conditions. The test is run on a blood sample.

Rates data updated October 2026.

How much does Prader-Willi/Angelman Genetic Test cost?

$38.90

Typical negotiated rate. In Illinois, October 2026.

Insurers have agreed to pay about $38.90 for this service. The price depends on where it is billed: about $38.90 from a physician practice, and about $95.50 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$38.90$23.44 to $43.65
FacilityA hospital or hospital-owned outpatient department$95.50$69.18 to $170

How much rates vary

Facilitymedian $95 · 10th to 90th $58 to $309Professionalmedian $39 · 10th to 90th $3 to $74
$5$10$20$50$100$200$500facility $95professional $39

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$43.65
Median
$79.43
Typical High
$154.88
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$20.89
Median
$39.81
Typical High
$77.62
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$8.32
Median
$15.85
Typical High
$30.90
Aetna
Setting
Professional
Modifier
None
Typical Low
$38.02
Median
$41.69
Typical High
$45.71
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$20.89
Median
$20.89
Typical High
$22.91
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$8.32
Median
$8.32
Typical High
$9.12
BCBS Illinois
Setting
Facility
Modifier
None
Typical Low
$61.66
Median
$89.13
Typical High
$645.65
BCBS Illinois
Setting
Professional
Modifier
None
Typical Low
$3.47
Median
$35.48
Typical High
$38.90
Cigna
Setting
Facility
Modifier
None
Typical Low
$57.54
Median
$107.15
Typical High
$213.80
Cigna
Setting
Professional
Modifier
None
Typical Low
$25.70
Median
$69.18
Typical High
$85.11
Hally Health
Setting
Professional
Modifier
None
Typical Low
$56.23
Median
$81.28
Typical High
$575.44
Hally Health
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$66.07
Typical High
$66.07
United
Setting
Facility
Modifier
None
Typical Low
$51.29
Median
$61.66
Typical High
$64.57
United
Setting
Professional
Modifier
None
Typical Low
$21.38
Median
$30.90
Typical High
$51.29

Where Illinois sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 47th of 51

$38.90

AK $115NE $33.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.