go back

Prader-Willi/Angelman Genetic Test

Iowa rates for HCPCS 81331

This service is a genetic laboratory test that looks at a specific pattern of gene activity to help diagnose Prader-Willi syndrome or Angelman syndrome, two different inherited conditions that affect development. It is typically ordered when a child shows developmental delay, low muscle tone, feeding difficulties, or other features suggestive of one of these conditions. The test is run on a blood sample.

Rates data updated October 2026.

How much does Prader-Willi/Angelman Genetic Test cost?

$54.95

Typical negotiated rate. In Iowa, October 2026.

Insurers have agreed to pay about $54.95 for this service. The price depends on where it is billed: about $51.29 from a physician practice, and about $95.50 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$51.29$30.90 to $97.72
FacilityA hospital or hospital-owned outpatient department$95.50$61.66 to $110

How much rates vary

Facilitymedian $95 · 10th to 90th $51 to $135Professionalmedian $51 · 10th to 90th $31 to $263
$20$50$100$200$500facility $95professional $51

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$39.81
Median
$107.15
Typical High
$144.54
Aetna
Setting
Professional
Modifier
None
Typical Low
$33.88
Median
$39.81
Typical High
$61.66
Cigna
Setting
Professional
Modifier
None
Typical Low
$63.10
Median
$97.72
Typical High
$123.03
Hally Health
Setting
Professional
Modifier
None
Typical Low
$56.23
Median
$89.13
Typical High
$537.03
Medica
Setting
Facility
Modifier
None
Typical Low
$51.29
Median
$97.72
Typical High
$117.49
Medica
Setting
Professional
Modifier
None
Typical Low
$30.90
Median
$61.66
Typical High
$263.03
Midlands
Setting
Professional
Modifier
None
Typical Low
$63.10
Median
$63.10
Typical High
$67.61
Oscar Health
Setting
Professional
Modifier
None
Typical Low
$51.29
Median
$54.95
Typical High
$109.65
United
Setting
Facility
Modifier
None
Typical Low
$51.29
Median
$51.29
Typical High
$131.83
United
Setting
Professional
Modifier
None
Typical Low
$30.90
Median
$30.90
Typical High
$104.71
Wellmark
Setting
Professional
Modifier
None
Typical Low
$51.29
Median
$51.29
Typical High
$51.29
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$19.95
Median
$19.95
Typical High
$30.90
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$7.94
Median
$7.94
Typical High
$12.30

Where Iowa sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 20th of 51

$54.95

AK $115NE $33.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.