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Prader-Willi/Angelman Genetic Test

Florida rates for HCPCS 81331

This service is a genetic laboratory test that looks at a specific pattern of gene activity to help diagnose Prader-Willi syndrome or Angelman syndrome, two different inherited conditions that affect development. It is typically ordered when a child shows developmental delay, low muscle tone, feeding difficulties, or other features suggestive of one of these conditions. The test is run on a blood sample.

Rates data updated July 2026.

How much does Prader-Willi/Angelman Genetic Test cost?

$45.71

Typical negotiated rate. In Florida, July 2026.

Insurers have agreed to pay about $45.71 for this service. The price depends on where it is billed: about $41.69 from a physician practice, and about $95.50 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$41.69$35.48 to $58.88
FacilityA hospital or hospital-owned outpatient department$95.50$45.71 to $148

How much rates vary

Facilitymedian $95 · 10th to 90th $38 to $251Professionalmedian $42 · 10th to 90th $31 to $59
$5.0$20.0$100.0$500.0$2.0Kfacility $95professional $42

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$38.02
Median
$125.89
Typical High
$275.42
Aetna
Setting
Professional
Modifier
Global
Typical Low
$35.48
Median
$43.65
Typical High
$58.88
AvMed
Setting
Facility
Modifier
Global
Typical Low
$44.67
Median
$51.29
Typical High
$60.26
AvMed
Setting
Professional
Modifier
Global
Typical Low
$14.13
Median
$51.29
Typical High
$51.29
Cigna
Setting
Facility
Modifier
Global
Typical Low
$47.86
Median
$69.18
Typical High
$208.93
Cigna
Setting
Professional
Modifier
Global
Typical Low
$24.55
Median
$41.69
Typical High
$91.20
Florida Blue
Setting
Facility
Modifier
Global
Typical Low
$95.50
Median
$95.50
Typical High
$95.50
Florida Blue
Setting
Professional
Modifier
Global
Typical Low
$30.90
Median
$30.90
Typical High
$40.74
Molina
Setting
Professional
Modifier
Global
Typical Low
$30.90
Median
$33.88
Typical High
$56.23
United
Setting
Facility
Modifier
Global
Typical Low
$21.38
Median
$45.71
Typical High
$51.29
United
Setting
Professional
Modifier
Global
Typical Low
$17.78
Median
$21.88
Typical High
$67.61
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$30.90
Median
$51.29
Typical High
$51.29

Where Florida sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Florida $45.71 · 41st of 51
AK $115MD $38.02

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.