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Prader-Willi/Angelman Genetic Test

Alabama rates for HCPCS 81331

This service is a genetic laboratory test that looks at a specific pattern of gene activity to help diagnose Prader-Willi syndrome or Angelman syndrome, two different inherited conditions that affect development. It is typically ordered when a child shows developmental delay, low muscle tone, feeding difficulties, or other features suggestive of one of these conditions. The test is run on a blood sample.

Rates data updated October 2026.

How much does Prader-Willi/Angelman Genetic Test cost?

$58.88

Typical negotiated rate. In Alabama, October 2026.

Insurers have agreed to pay about $58.88 for this service. The price depends on where it is billed: about $30.90 from a physician practice, and about $63.10 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$30.90$23.44 to $58.88
FacilityA hospital or hospital-owned outpatient department$63.10$63.10 to $63.10

How much rates vary

Facilitymedian $63 · 10th to 90th $59 to $63Professionalmedian $31 · 10th to 90th $21 to $59
$20$50$100facility $63professional $31

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$58.88
Median
$58.88
Typical High
$79.43
Aetna
Setting
Professional
Modifier
None
Typical Low
$37.15
Median
$58.88
Typical High
$58.88
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$19.95
Median
$29.51
Typical High
$29.51
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$7.94
Median
$11.75
Typical High
$11.75
BCBS Alabama
Setting
Facility
Modifier
None
Typical Low
$63.10
Median
$63.10
Typical High
$63.10
BCBS Alabama
Setting
Professional
Modifier
21 + 22 · Increased work + 24 · Unrelated visit after surgery + 31
Typical Low
$48.98
Median
$263.03
Typical High
$263.03
Cigna
Setting
Facility
Modifier
None
Typical Low
$41.69
Median
$43.65
Typical High
$162.18
Cigna
Setting
Professional
Modifier
None
Typical Low
$21.88
Median
$23.44
Typical High
$30.90
United
Setting
Facility
Modifier
None
Typical Low
$18.20
Median
$45.71
Typical High
$51.29
United
Setting
Professional
Modifier
None
Typical Low
$21.38
Median
$28.18
Typical High
$30.90

Where Alabama sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 13th of 51

$58.88

AK $115NE $33.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.