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SMPD1 Gene Test For Niemann-Pick Disease

Virginia rates for HCPCS 81330

A laboratory test on a blood sample that checks the SMPD1 gene for a set of well-recognized changes. When both copies of this gene are altered, a fatty substance builds up inside the body's cells, causing Niemann-Pick disease.

Rates data updated July 2026.

How much does SMPD1 Gene Test For Niemann-Pick Disease cost?

$39.81

Typical negotiated rate. In Virginia, July 2026.

Insurers have agreed to pay about $39.81 for this service. The price depends on where it is billed: about $35.48 from a physician practice, and about $50.12 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$35.48$22.39 to $39.81
FacilityA hospital or hospital-owned outpatient department$50.12$46.77 to $105

How much rates vary

Facilitymedian $50 · 10th to 90th $40 to $234Professionalmedian $35 · 10th to 90th $19 to $89
$20$100$500$2K$10Kfacility $50professional $35

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$35.48
Median
$89.13
Typical High
$186.21
Aetna
Setting
Professional
Modifier
Global
Typical Low
$32.36
Median
$38.90
Typical High
$91.20
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$46.77
Median
$46.77
Typical High
$186.21
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$18.62
Median
$18.62
Typical High
$31.62
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$42.66
Median
$416.87
Typical High
$630.96
Cigna
Setting
Facility
Modifier
Global
Typical Low
$47.86
Median
$104.71
Typical High
$213.80
Cigna
Setting
Professional
Modifier
Global
Typical Low
$23.44
Median
$28.84
Typical High
$83.18
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$46.77
Median
$51.29
Typical High
$66.07
Medcost
Setting
Facility
Modifier
Global
Typical Low
$37.15
Median
$63.10
Typical High
$269.15
Medcost
Setting
Professional
Modifier
Global
Typical Low
$30.90
Median
$97.72
Typical High
$269.15
Sentara
Setting
Facility
Modifier
Global
Typical Low
$42.66
Median
$67.61
Typical High
$10,000.00
Sentara
Setting
Professional
Modifier
Global
Typical Low
$42.66
Median
$67.61
Typical High
$10,000.00
United
Setting
Facility
Modifier
Global
Typical Low
$28.18
Median
$46.77
Typical High
$56.23
United
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$23.99
Typical High
$53.70

Where Virginia sits

The same service costs 3.0 times more in Alaska than in New Mexico. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 37th of 51

$39.81

AK $105NM $35.48

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.