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SMPD1 Gene Test For Niemann-Pick Disease

South Carolina rates for HCPCS 81330

A laboratory test on a blood sample that checks the SMPD1 gene for a set of well-recognized changes. When both copies of this gene are altered, a fatty substance builds up inside the body's cells, causing Niemann-Pick disease.

Rates data updated July 2026.

How much does SMPD1 Gene Test For Niemann-Pick Disease cost?

$38.02

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $38.02 for this service. The price depends on where it is billed: about $38.02 from a physician practice, and about $87.10 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$38.02$36.31 to $40.74
FacilityA hospital or hospital-owned outpatient department$87.10$36.31 to $151

How much rates vary

Facilitymedian $87 · 10th to 90th $36 to $224Professionalmedian $38 · 10th to 90th $31 to $56
$20$50$100$200facility $87professional $38

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$33.11
Median
$114.82
Typical High
$223.87
Aetna
Setting
Professional
Modifier
Global
Typical Low
$36.31
Median
$36.31
Typical High
$42.66
BCBS
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$288.40
Typical High
$309.03
BCBS
Setting
Professional
Modifier
Global
Typical Low
$47.86
Median
$85.11
Typical High
$123.03
Cigna
Setting
Facility
Modifier
Global
Typical Low
$89.13
Median
$141.25
Typical High
$269.15
Cigna
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$25.70
Typical High
$100.00
Medcost
Setting
Facility
Modifier
Global
Typical Low
$36.31
Median
$44.67
Typical High
$134.90
United
Setting
Facility
Modifier
Global
Typical Low
$42.66
Median
$46.77
Typical High
$56.23
United
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$28.18
Typical High
$46.77

Where South Carolina sits

The same service costs 3.0 times more in Alaska than in New Mexico. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 47th of 51

$38.02

AK $105NM $35.48

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.