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SMPD1 Gene Test For Niemann-Pick Disease

Ohio rates for HCPCS 81330

A laboratory test on a blood sample that checks the SMPD1 gene for a set of well-recognized changes. When both copies of this gene are altered, a fatty substance builds up inside the body's cells, causing Niemann-Pick disease.

Rates data updated July 2026.

How much does SMPD1 Gene Test For Niemann-Pick Disease cost?

$43.65

Typical negotiated rate. In Ohio, July 2026.

Insurers have agreed to pay about $43.65 for this service. The price depends on where it is billed: about $38.02 from a physician practice, and about $63.10 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$38.02$25.12 to $46.77
FacilityA hospital or hospital-owned outpatient department$63.10$46.77 to $102

How much rates vary

Facilitymedian $63 · 10th to 90th $38 to $186Professionalmedian $38 · 10th to 90th $19 to $117
$20$50$100$200facility $63professional $38

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$38.02
Median
$85.11
Typical High
$186.21
Aetna
Setting
Professional
Modifier
Global
Typical Low
$38.02
Median
$38.02
Typical High
$134.90
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$42.66
Median
$50.12
Typical High
$87.10
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$18.62
Median
$23.99
Typical High
$87.10
CareSource
Setting
Facility
Modifier
Global
Typical Low
$53.70
Median
$53.70
Typical High
$53.70
CareSource
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$63.10
Typical High
$63.10
Cigna
Setting
Facility
Modifier
Global
Typical Low
$45.71
Median
$61.66
Typical High
$239.88
Cigna
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$41.69
Typical High
$104.71
Medical Mutual of Ohio
Setting
Facility
Modifier
Global
Typical Low
$46.77
Median
$61.66
Typical High
$194.98
Medical Mutual of Ohio
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$25.70
Typical High
$100.00
Molina
Setting
Professional
Modifier
Global
Typical Low
$32.36
Median
$42.66
Typical High
$51.29
SummaCare
Setting
Professional
Modifier
Global
Typical Low
$39.81
Median
$52.48
Typical High
$109.65
United
Setting
Facility
Modifier
Global
Typical Low
$28.18
Median
$46.77
Typical High
$70.79
United
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$28.18
Typical High
$64.57

Where Ohio sits

The same service costs 3.0 times more in Alaska than in New Mexico. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Ohio· 34th of 51

$43.65

AK $105NM $35.48

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.