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SMPD1 Gene Test For Niemann-Pick Disease

New York rates for HCPCS 81330

A laboratory test on a blood sample that checks the SMPD1 gene for a set of well-recognized changes. When both copies of this gene are altered, a fatty substance builds up inside the body's cells, causing Niemann-Pick disease.

Rates data updated July 2026.

How much does SMPD1 Gene Test For Niemann-Pick Disease cost?

$48.98

Typical negotiated rate. In New York, July 2026.

Insurers have agreed to pay about $48.98 for this service. The price depends on where it is billed: about $41.69 from a physician practice, and about $83.18 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$41.69$28.18 to $70.79
FacilityA hospital or hospital-owned outpatient department$83.18$50.12 to $112

How much rates vary

Facilitymedian $83 · 10th to 90th $46 to $135Professionalmedian $42 · 10th to 90th $19 to $120
$20$50$100$200$500$1Kfacility $83professional $42

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$46.77
Median
$83.18
Typical High
$128.82
Aetna
Setting
Professional
Modifier
Global
Typical Low
$33.11
Median
$46.77
Typical High
$134.90
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$46.77
Median
$46.77
Typical High
$123.03
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$18.62
Median
$18.62
Typical High
$91.20
CDPHP
Setting
Facility
Modifier
Global
Typical Low
$28.18
Median
$46.77
Typical High
$46.77
CDPHP
Setting
Professional
Modifier
Global
Typical Low
$46.77
Median
$46.77
Typical High
$93.33
Cigna
Setting
Facility
Modifier
Global
Typical Low
$45.71
Median
$100.00
Typical High
$223.87
Cigna
Setting
Professional
Modifier
Global
Typical Low
$28.18
Median
$66.07
Typical High
$229.09
Emblem Health
Setting
Facility
Modifier
Global
Typical Low
$53.70
Median
$128.82
Typical High
$269.15
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$28.18
Median
$39.81
Typical High
$89.13
Excellus BCBS
Setting
Professional
Modifier
Global
Typical Low
$38.02
Median
$44.67
Typical High
$83.18
MVP Health Care
Setting
Facility
Modifier
Global
Typical Low
$13.80
Median
$89.13
Typical High
$257.04
MVP Health Care
Setting
Professional
Modifier
Global
Typical Low
$46.77
Median
$46.77
Typical High
$97.72
United
Setting
Facility
Modifier
Global
Typical Low
$42.66
Median
$46.77
Typical High
$70.79
United
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$43.65
Typical High
$154.88
Univera
Setting
Facility
Modifier
Global
Typical Low
$39.81
Median
$39.81
Typical High
$50.12
Univera
Setting
Professional
Modifier
Global
Typical Low
$38.02
Median
$44.67
Typical High
$112.20

Where New York sits

The same service costs 3.0 times more in Alaska than in New Mexico. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

New York· 20th of 51

$48.98

AK $105NM $35.48

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.