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SMPD1 Gene Test For Niemann-Pick Disease

North Carolina rates for HCPCS 81330

A laboratory test on a blood sample that checks the SMPD1 gene for a set of well-recognized changes. When both copies of this gene are altered, a fatty substance builds up inside the body's cells, causing Niemann-Pick disease.

Rates data updated July 2026.

How much does SMPD1 Gene Test For Niemann-Pick Disease cost?

$38.02

Typical negotiated rate. In North Carolina, July 2026.

Insurers have agreed to pay about $38.02 for this service. The price depends on where it is billed: about $38.02 from a physician practice, and about $44.67 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$38.02$33.88 to $51.29
FacilityA hospital or hospital-owned outpatient department$44.67$38.02 to $81.28

How much rates vary

Facilitymedian $45 · 10th to 90th $36 to $155Professionalmedian $38 · 10th to 90th $22 to $66
$20$50$100$200facility $45professional $38

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$29.51
Median
$41.69
Typical High
$154.88
Aetna
Setting
Professional
Modifier
Global
Typical Low
$30.90
Median
$38.02
Typical High
$61.66
BCBS
Setting
Facility
Modifier
Global
Typical Low
$107.15
Median
$141.25
Typical High
$141.25
BCBS
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$42.66
Typical High
$75.86
Cigna
Setting
Facility
Modifier
Global
Typical Low
$32.36
Median
$102.33
Typical High
$213.80
Cigna
Setting
Professional
Modifier
Global
Typical Low
$21.88
Median
$22.39
Typical High
$63.10
Medcost
Setting
Facility
Modifier
Global
Typical Low
$38.02
Median
$47.86
Typical High
$89.13
Medcost
Setting
Professional
Modifier
Global
Typical Low
$218.78
Median
$218.78
Typical High
$218.78
United
Setting
Facility
Modifier
Global
Typical Low
$28.18
Median
$54.95
Typical High
$57.54
United
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$28.18
Typical High
$51.29
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$223.87
Median
$223.87
Typical High
$223.87
Wellcare
Setting
Professional
Modifier
Global
Typical Low
$234.42
Median
$234.42
Typical High
$354.81

Where North Carolina sits

The same service costs 3.0 times more in Alaska than in New Mexico. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 48th of 51

$38.02

AK $105NM $35.48

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.