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SMPD1 Gene Test For Niemann-Pick Disease

Mississippi rates for HCPCS 81330

A laboratory test on a blood sample that checks the SMPD1 gene for a set of well-recognized changes. When both copies of this gene are altered, a fatty substance builds up inside the body's cells, causing Niemann-Pick disease.

Rates data updated July 2026.

How much does SMPD1 Gene Test For Niemann-Pick Disease cost?

$53.70

Typical negotiated rate. In Mississippi, July 2026.

Insurers have agreed to pay about $53.70 for this service. The price depends on where it is billed: about $50.12 from a physician practice, and about $85.11 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$50.12$35.48 to $85.11
FacilityA hospital or hospital-owned outpatient department$85.11$46.77 to $95.50

How much rates vary

Facilitymedian $85 · 10th to 90th $43 to $135Professionalmedian $50 · 10th to 90th $28 to $95
$20$50$100facility $85professional $50

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$46.77
Median
$85.11
Typical High
$95.50
Aetna
Setting
Professional
Modifier
Global
Typical Low
$35.48
Median
$53.70
Typical High
$95.50
BCBS
Setting
Facility
Modifier
Global
Typical Low
$134.90
Median
$134.90
Typical High
$134.90
BCBS
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$104.71
Typical High
$104.71
Cigna
Setting
Facility
Modifier
Global
Typical Low
$30.90
Median
$35.48
Typical High
$74.13
Cigna
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$21.38
Typical High
$87.10
United
Setting
Facility
Modifier
Global
Typical Low
$42.66
Median
$42.66
Typical High
$46.77
United
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$28.18
Typical High
$79.43

Where Mississippi sits

The same service costs 3.0 times more in Alaska than in New Mexico. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Mississippi· 15th of 51

$53.70

AK $105NM $35.48

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.