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SMPD1 Gene Test For Niemann-Pick Disease

Missouri rates for HCPCS 81330

A laboratory test on a blood sample that checks the SMPD1 gene for a set of well-recognized changes. When both copies of this gene are altered, a fatty substance builds up inside the body's cells, causing Niemann-Pick disease.

Rates data updated July 2026.

How much does SMPD1 Gene Test For Niemann-Pick Disease cost?

$46.77

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $46.77 for this service. The price depends on where it is billed: about $40.74 from a physician practice, and about $61.66 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$40.74$28.18 to $56.23
FacilityA hospital or hospital-owned outpatient department$61.66$46.77 to $81.28

How much rates vary

Facilitymedian $62 · 10th to 90th $44 to $110Professionalmedian $41 · 10th to 90th $19 to $91
$20$50$100$200facility $62professional $41

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$45.71
Median
$79.43
Typical High
$109.65
Aetna
Setting
Professional
Modifier
Global
Typical Low
$39.81
Median
$45.71
Typical High
$95.50
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$46.77
Median
$46.77
Typical High
$165.96
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$18.62
Median
$28.84
Typical High
$83.18
BCBS
Setting
Facility
Modifier
Global
Typical Low
$64.57
Median
$69.18
Typical High
$123.03
BCBS
Setting
Professional
Modifier
Global
Typical Low
$33.11
Median
$46.77
Typical High
$52.48
Cigna
Setting
Facility
Modifier
Global
Typical Low
$34.67
Median
$91.20
Typical High
$141.25
Cigna
Setting
Professional
Modifier
Global
Typical Low
$21.38
Median
$36.31
Typical High
$67.61
Medica
Setting
Facility
Modifier
Global
Typical Low
$40.74
Median
$58.88
Typical High
$223.87
Medica
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$28.18
Typical High
$234.42
United
Setting
Facility
Modifier
Global
Typical Low
$19.95
Median
$46.77
Typical High
$56.23
United
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$28.18
Typical High
$63.10

Where Missouri sits

The same service costs 3.0 times more in Alaska than in New Mexico. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 26th of 51

$46.77

AK $105NM $35.48

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.