go back

SMPD1 Gene Test For Niemann-Pick Disease

Massachusetts rates for HCPCS 81330

A laboratory test on a blood sample that checks the SMPD1 gene for a set of well-recognized changes. When both copies of this gene are altered, a fatty substance builds up inside the body's cells, causing Niemann-Pick disease.

Rates data updated July 2026.

How much does SMPD1 Gene Test For Niemann-Pick Disease cost?

$46.77

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $46.77 for this service. The price depends on where it is billed: about $46.77 from a physician practice, and about $93.33 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$46.77$46.77 to $83.18
FacilityA hospital or hospital-owned outpatient department$93.33$74.13 to $135

How much rates vary

Facilitymedian $93 · 10th to 90th $51 to $151Professionalmedian $47 · 10th to 90th $32 to $135
$50$100$200$500$1K$2K$5Kfacility $93professional $47

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$46.77
Median
$104.71
Typical High
$141.25
Aetna
Setting
Professional
Modifier
Global
Typical Low
$32.36
Median
$83.18
Typical High
$134.90
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$51.29
Median
$147.91
Typical High
$223.87
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$28.18
Median
$46.77
Typical High
$138.04
BCBS
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$93.33
Typical High
$134.90
BCBS
Setting
Professional
Modifier
Global
Typical Low
$64.57
Median
$64.57
Typical High
$64.57
Cigna
Setting
Facility
Modifier
Global
Typical Low
$30.90
Median
$57.54
Typical High
$91.20
Cigna
Setting
Professional
Modifier
Global
Typical Low
$25.70
Median
$50.12
Typical High
$123.03
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$3,630.78
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$35.48
Median
$67.61
Typical High
$79.43
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$46.77
Median
$46.77
Typical High
$85.11
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$51.29
Median
$147.91
Typical High
$223.87
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$28.18
Median
$46.77
Typical High
$138.04
United
Setting
Facility
Modifier
Global
Typical Low
$28.18
Median
$46.77
Typical High
$56.23
United
Setting
Professional
Modifier
Global
Typical Low
$28.18
Median
$46.77
Typical High
$107.15

Where Massachusetts sits

The same service costs 3.0 times more in Alaska than in New Mexico. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 23rd of 51

$46.77

AK $105NM $35.48

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.