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SMPD1 Gene Test For Niemann-Pick Disease

Indiana rates for HCPCS 81330

A laboratory test on a blood sample that checks the SMPD1 gene for a set of well-recognized changes. When both copies of this gene are altered, a fatty substance builds up inside the body's cells, causing Niemann-Pick disease.

Rates data updated July 2026.

How much does SMPD1 Gene Test For Niemann-Pick Disease cost?

$38.90

Typical negotiated rate. In Indiana, July 2026.

Insurers have agreed to pay about $38.90 for this service. The price depends on where it is billed: about $38.90 from a physician practice, and about $46.77 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$38.90$32.36 to $38.90
FacilityA hospital or hospital-owned outpatient department$46.77$46.77 to $93.33

How much rates vary

Facilitymedian $47 · 10th to 90th $47 to $141Professionalmedian $39 · 10th to 90th $19 to $54
$20$50$100$200$500facility $47professional $39

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$38.90
Median
$52.48
Typical High
$141.25
Aetna
Setting
Professional
Modifier
Global
Typical Low
$35.48
Median
$38.90
Typical High
$44.67
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$46.77
Median
$46.77
Typical High
$141.25
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$18.62
Median
$18.62
Typical High
$87.10
Cigna
Setting
Facility
Modifier
Global
Typical Low
$46.77
Median
$46.77
Typical High
$109.65
Cigna
Setting
Professional
Modifier
Global
Typical Low
$24.55
Median
$42.66
Typical High
$67.61
United
Setting
Facility
Modifier
Global
Typical Low
$46.77
Median
$46.77
Typical High
$53.70
United
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$28.18
Typical High
$56.23

Where Indiana sits

The same service costs 3.0 times more in Alaska than in New Mexico. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 41st of 51

$38.90

AK $105NM $35.48

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.