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SMPD1 Gene Test For Niemann-Pick Disease

Iowa rates for HCPCS 81330

A laboratory test on a blood sample that checks the SMPD1 gene for a set of well-recognized changes. When both copies of this gene are altered, a fatty substance builds up inside the body's cells, causing Niemann-Pick disease.

Rates data updated July 2026.

How much does SMPD1 Gene Test For Niemann-Pick Disease cost?

$46.77

Typical negotiated rate. In Iowa, July 2026.

Insurers have agreed to pay about $46.77 for this service. The price depends on where it is billed: about $40.74 from a physician practice, and about $74.13 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$40.74$36.31 to $91.20
FacilityA hospital or hospital-owned outpatient department$74.13$46.77 to $123

How much rates vary

Facilitymedian $74 · 10th to 90th $36 to $135Professionalmedian $41 · 10th to 90th $28 to $309
$50$100$200facility $74professional $41

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$36.31
Median
$97.72
Typical High
$134.90
Aetna
Setting
Professional
Modifier
Global
Typical Low
$30.90
Median
$40.74
Typical High
$309.03
Cigna
Setting
Facility
Modifier
Global
Typical Low
$223.87
Median
$223.87
Typical High
$223.87
Cigna
Setting
Professional
Modifier
Global
Typical Low
$60.26
Median
$91.20
Typical High
$112.20
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$58.88
Median
$125.89
Typical High
$154.88
Medica
Setting
Facility
Modifier
Global
Typical Low
$46.77
Median
$56.23
Typical High
$125.89
Medica
Setting
Professional
Modifier
Global
Typical Low
$28.18
Median
$47.86
Typical High
$186.21
Midlands
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$61.66
Typical High
$61.66
Oscar Health
Setting
Professional
Modifier
Global
Typical Low
$46.77
Median
$51.29
Typical High
$100.00
United
Setting
Facility
Modifier
Global
Typical Low
$46.77
Median
$46.77
Typical High
$104.71
United
Setting
Professional
Modifier
Global
Typical Low
$28.18
Median
$28.18
Typical High
$120.23
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$46.77
Median
$46.77
Typical High
$46.77

Where Iowa sits

The same service costs 3.0 times more in Alaska than in New Mexico. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 25th of 51

$46.77

AK $105NM $35.48

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.