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SMPD1 Gene Test For Niemann-Pick Disease

Washington, DC rates for HCPCS 81330

A laboratory test on a blood sample that checks the SMPD1 gene for a set of well-recognized changes. When both copies of this gene are altered, a fatty substance builds up inside the body's cells, causing Niemann-Pick disease.

Rates data updated July 2026.

How much does SMPD1 Gene Test For Niemann-Pick Disease cost?

$35.48

Typical negotiated rate. In Washington, DC, July 2026.

Insurers have agreed to pay about $35.48 for this service. The price depends on where it is billed: about $35.48 from a physician practice, and about $35.48 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$35.48$34.67 to $36.31
FacilityA hospital or hospital-owned outpatient department$35.48$35.48 to $56.23

How much rates vary

Facilitymedian $35 · 10th to 90th $35 to $79Professionalmedian $35 · 10th to 90th $35 to $107
$20$50$100$200$500$1Kfacility $35professional $35

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$35.48
Median
$35.48
Typical High
$35.48
Aetna
Setting
Professional
Modifier
Global
Typical Low
$34.67
Median
$35.48
Typical High
$36.31
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$38.02
Median
$288.40
Typical High
$1,000.00
Cigna
Setting
Facility
Modifier
Global
Typical Low
$75.86
Median
$79.43
Typical High
$181.97
Cigna
Setting
Professional
Modifier
Global
Typical Low
$20.89
Median
$60.26
Typical High
$213.80
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$53.70
Median
$81.28
Typical High
$95.50
United
Setting
Facility
Modifier
Global
Typical Low
$19.95
Median
$56.23
Typical High
$56.23
United
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$21.38
Typical High
$44.67

Where Washington, DC sits

The same service costs 3.0 times more in Alaska than in New Mexico. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Washington, DC· 50th of 51

$35.48

AK $105NM $35.48

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.