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SMPD1 Gene Test For Niemann-Pick Disease

Colorado rates for HCPCS 81330

A laboratory test on a blood sample that checks the SMPD1 gene for a set of well-recognized changes. When both copies of this gene are altered, a fatty substance builds up inside the body's cells, causing Niemann-Pick disease.

Rates data updated July 2026.

How much does SMPD1 Gene Test For Niemann-Pick Disease cost?

$60.26

Typical negotiated rate. In Colorado, July 2026.

Insurers have agreed to pay about $60.26 for this service. The price depends on where it is billed: about $35.48 from a physician practice, and about $115 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$35.48$28.18 to $38.90
FacilityA hospital or hospital-owned outpatient department$115$63.10 to $195

How much rates vary

Facilitymedian $115 · 10th to 90th $36 to $240Professionalmedian $35 · 10th to 90th $20 to $58
$20$50$100$200facility $115professional $35

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$29.51
Median
$102.33
Typical High
$218.78
Aetna
Setting
Professional
Modifier
Global
Typical Low
$31.62
Median
$35.48
Typical High
$50.12
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$58.88
Median
$141.25
Typical High
$239.88
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$19.95
Typical High
$61.66
Cigna
Setting
Facility
Modifier
Global
Typical Low
$27.54
Median
$30.90
Typical High
$123.03
Cigna
Setting
Professional
Modifier
Global
Typical Low
$21.88
Median
$25.12
Typical High
$69.18
Denver HMP
Setting
Facility
Modifier
Global
Typical Low
$35.48
Median
$46.77
Typical High
$72.44
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$66.07
Typical High
$213.80
Select Health
Setting
Facility
Modifier
Global
Typical Low
$48.98
Median
$87.10
Typical High
$97.72
Select Health
Setting
Professional
Modifier
Global
Typical Low
$33.11
Median
$46.77
Typical High
$70.79
United
Setting
Facility
Modifier
Global
Typical Low
$42.66
Median
$46.77
Typical High
$70.79
United
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$19.95
Typical High
$28.18

Where Colorado sits

The same service costs 3.0 times more in Alaska than in New Mexico. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 6th of 51

$60.26

AK $105NM $35.48

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.