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SMPD1 Gene Test For Niemann-Pick Disease

Alabama rates for HCPCS 81330

A laboratory test on a blood sample that checks the SMPD1 gene for a set of well-recognized changes. When both copies of this gene are altered, a fatty substance builds up inside the body's cells, causing Niemann-Pick disease.

Rates data updated July 2026.

How much does SMPD1 Gene Test For Niemann-Pick Disease cost?

$53.70

Typical negotiated rate. In Alabama, July 2026.

Insurers have agreed to pay about $53.70 for this service. The price depends on where it is billed: about $39.81 from a physician practice, and about $58.88 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$39.81$30.90 to $53.70
FacilityA hospital or hospital-owned outpatient department$58.88$46.77 to $74.13

How much rates vary

Facilitymedian $59 · 10th to 90th $43 to $89Professionalmedian $40 · 10th to 90th $28 to $54
$20$50$100facility $59professional $40

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$46.77
Median
$53.70
Typical High
$72.44
Aetna
Setting
Professional
Modifier
Global
Typical Low
$28.18
Median
$39.81
Typical High
$53.70
BCBS
Setting
Facility
Modifier
Global
Typical Low
$58.88
Median
$70.79
Typical High
$95.50
BCBS
Setting
Professional
Modifier
Global
Typical Low
$44.67
Median
$75.86
Typical High
$117.49
Cigna
Setting
Facility
Modifier
Global
Typical Low
$30.90
Median
$39.81
Typical High
$147.91
Cigna
Setting
Professional
Modifier
Global
Typical Low
$20.42
Median
$20.89
Typical High
$100.00
United
Setting
Facility
Modifier
Global
Typical Low
$19.95
Median
$42.66
Typical High
$46.77
United
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$19.95
Typical High
$46.77

Where Alabama sits

The same service costs 3.0 times more in Alaska than in New Mexico. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 13th of 51

$53.70

AK $105NM $35.48

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.