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Full Gene Test For Inherited Tumor Risk

Pennsylvania rates for HCPCS 81321

A laboratory test that reads the entire sequence of a single gene from a blood sample, looking for inherited changes linked to a higher risk of tumors. Reading the whole gene picks up changes anywhere along it, not only at the spots a shorter test checks.

Rates data updated October 2026.

How much does Full Gene Test For Inherited Tumor Risk cost?

$490

Typical negotiated rate. In Pennsylvania, October 2026.

Insurers have agreed to pay about $490 for this service. The price depends on where it is billed: about $490 from a physician practice, and about $724 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$490$457 to $603
FacilityA hospital or hospital-owned outpatient department$724$603 to $1,148

How much rates vary

Facilitymedian $724 · 10th to 90th $490 to $1,820Professionalmedian $490 · 10th to 90th $324 to $891
$500$1K$2K$5K$10K$20K$50Kfacility $724professional $490

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$489.78
Median
$512.86
Typical High
$1,737.80
Aetna
Setting
Professional
Modifier
None
Typical Low
$457.09
Median
$489.78
Typical High
$512.86
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$234.42
Median
$245.47
Typical High
$257.04
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$95.50
Median
$97.72
Typical High
$102.33
Capital Blue Cross
Setting
Facility
Modifier
None
Typical Low
$4,265.80
Median
$5,011.87
Typical High
$79,432.82
Capital Blue Cross
Setting
Professional
Modifier
None
Typical Low
$426.58
Median
$467.74
Typical High
$1,445.44
Cigna
Setting
Facility
Modifier
None
Typical Low
$588.84
Median
$977.24
Typical High
$1,819.70
Cigna
Setting
Professional
Modifier
None
Typical Low
$281.84
Median
$645.65
Typical High
$933.25
Emblem Health
Setting
Professional
Modifier
None
Typical Low
$416.87
Median
$794.33
Typical High
$794.33
Geisinger
Setting
Facility
Modifier
None
Typical Low
$602.56
Median
$602.56
Typical High
$602.56
Geisinger
Setting
Professional
Modifier
None
Typical Low
$602.56
Median
$933.25
Typical High
$1,513.56
Martin's Point
Setting
Facility
Modifier
None
Typical Low
$489.78
Median
$489.78
Typical High
$1,737.80
Martin's Point
Setting
Professional
Modifier
None
Typical Low
$478.63
Median
$489.78
Typical High
$512.86
Martin's Point
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$234.42
Median
$245.47
Typical High
$257.04
Martin's Point
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$95.50
Median
$97.72
Typical High
$102.33
UPMC Health Plan
Setting
Facility
Modifier
None
Typical Low
$602.56
Median
$660.69
Typical High
$1,479.11
UPMC Health Plan
Setting
Professional
Modifier
None
Typical Low
$602.56
Median
$660.69
Typical High
$660.69
United
Setting
Facility
Modifier
None
Typical Low
$537.03
Median
$602.56
Typical High
$724.44
United
Setting
Professional
Modifier
None
Typical Low
$251.19
Median
$363.08
Typical High
$724.44

Where Pennsylvania sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 39th of 51

$490

AK $1,349NE $398

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.