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Full Gene Test For Inherited Tumor Risk

Pennsylvania rates for HCPCS 81321

A laboratory test that reads the entire sequence of a single gene from a blood sample, looking for inherited changes linked to a higher risk of tumors. Reading the whole gene picks up changes anywhere along it, not only at the spots a shorter test checks.

Rates data updated July 2026.

How much does Full Gene Test For Inherited Tumor Risk cost?

$513

Typical negotiated rate. In Pennsylvania, July 2026.

Insurers have agreed to pay about $513 for this service. The price depends on where it is billed: about $490 from a physician practice, and about $1,148 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$490$457 to $562
FacilityA hospital or hospital-owned outpatient department$1,148$724 to $1,514

How much rates vary

Facilitymedian $1,148 · 10th to 90th $513 to $2,089Professionalmedian $490 · 10th to 90th $324 to $1,413
$500$1K$2Kfacility $1,148professional $490

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$512.86
Median
$1,148.15
Typical High
$2,089.30
Aetna
Setting
Professional
Modifier
Global
Typical Low
$363.08
Median
$489.78
Typical High
$1,778.28
Capital Blue Cross
Setting
Facility
Modifier
Global
Typical Low
$5,011.87
Median
$8,511.38
Typical High
$77,624.71
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$467.74
Median
$467.74
Typical High
$467.74
Cigna
Setting
Facility
Modifier
Global
Typical Low
$588.84
Median
$977.24
Typical High
$2,041.74
Cigna
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$575.44
Typical High
$1,348.96
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$416.87
Median
$416.87
Typical High
$794.33
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$602.56
Median
$602.56
Typical High
$602.56
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$575.44
Median
$954.99
Typical High
$1,513.56
Highmark BCBS
Setting
Facility
Modifier
Global
Typical Low
$239.88
Median
$239.88
Typical High
$239.88
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$489.78
Median
$1,148.15
Typical High
$2,137.96
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$363.08
Median
$489.78
Typical High
$2,137.96
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$602.56
Median
$1,023.29
Typical High
$1,096.48
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$602.56
Median
$602.56
Typical High
$660.69
United
Setting
Facility
Modifier
Global
Typical Low
$537.03
Median
$602.56
Typical High
$724.44
United
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$363.08
Typical High
$891.25

Where Pennsylvania sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 37th of 51

$513

AK $1,349MD $447

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.