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Full Gene Test For Inherited Tumor Risk

Pennsylvania rates for HCPCS 81321

A laboratory test that reads the entire sequence of a single gene from a blood sample, looking for inherited changes linked to a higher risk of tumors. Reading the whole gene picks up changes anywhere along it, not only at the spots a shorter test checks.

Rates data updated July 2026.

Facilitymedian $1,148 · 10th–90th $513$2,0890%10%10th90th$1,148Professionalmedian $490 · 10th–90th $324$1,4130%20%10th90th$490$500.0$1.0K$2.0K$5.0K$10.0K$20.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$512.86
Median
$1,148.15
Typical High
$2,089.30
Aetna
Setting
Professional
Modifier
Global
Typical Low
$363.08
Median
$489.78
Typical High
$1,778.28
Capital Blue Cross
Setting
Facility
Modifier
Global
Typical Low
$5,011.87
Median
$8,511.38
Typical High
$77,624.71
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$467.74
Median
$467.74
Typical High
$467.74
Cigna
Setting
Facility
Modifier
Global
Typical Low
$588.84
Median
$977.24
Typical High
$2,041.74
Cigna
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$575.44
Typical High
$1,348.96
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$416.87
Median
$416.87
Typical High
$794.33
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$602.56
Median
$602.56
Typical High
$602.56
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$575.44
Median
$954.99
Typical High
$1,513.56
Highmark BCBS
Setting
Facility
Modifier
Global
Typical Low
$239.88
Median
$239.88
Typical High
$239.88
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$489.78
Median
$1,148.15
Typical High
$2,137.96
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$363.08
Median
$489.78
Typical High
$2,137.96
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$602.56
Median
$1,023.29
Typical High
$1,096.48
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$602.56
Median
$602.56
Typical High
$660.69
United
Setting
Facility
Modifier
Global
Typical Low
$537.03
Median
$602.56
Typical High
$724.44
United
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$363.08
Typical High
$891.25