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Full Gene Test For Inherited Tumor Risk

North Carolina rates for HCPCS 81321

A laboratory test that reads the entire sequence of a single gene from a blood sample, looking for inherited changes linked to a higher risk of tumors. Reading the whole gene picks up changes anywhere along it, not only at the spots a shorter test checks.

Rates data updated October 2026.

How much does Full Gene Test For Inherited Tumor Risk cost?

$537

Typical negotiated rate. In North Carolina, October 2026.

Insurers have agreed to pay about $537 for this service. The price depends on where it is billed: about $537 from a physician practice, and about $1,175 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$537$479 to $631
FacilityA hospital or hospital-owned outpatient department$1,175$479 to $1,905

How much rates vary

Facilitymedian $1,175 · 10th to 90th $479 to $2,754Professionalmedian $537 · 10th to 90th $282 to $1,023
$500$1K$2Kfacility $1,175professional $537

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$478.63
Median
$478.63
Typical High
$1,000.00
Aetna
Setting
Professional
Modifier
None
Typical Low
$467.74
Median
$478.63
Typical High
$724.44
BCBS North Carolina
Setting
Facility
Modifier
None
Typical Low
$1,318.26
Median
$1,348.96
Typical High
$1,905.46
BCBS North Carolina
Setting
Professional
Modifier
None
Typical Low
$389.05
Median
$537.03
Typical High
$1,288.25
Cigna
Setting
Facility
Modifier
None
Typical Low
$457.09
Median
$1,318.26
Typical High
$2,754.23
Cigna
Setting
Professional
Modifier
None
Typical Low
$275.42
Median
$537.03
Typical High
$812.83
Medcost
Setting
Facility
Modifier
None
Typical Low
$478.63
Median
$478.63
Typical High
$707.95
Medcost
Setting
Professional
Modifier
None
Typical Low
$602.56
Median
$602.56
Typical High
$1,023.29
United
Setting
Professional
Modifier
None
Typical Low
$251.19
Median
$363.08
Typical High
$616.60
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$234.42
Median
$239.88
Typical High
$363.08
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$93.33
Median
$95.50
Typical High
$144.54
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$302.00
Median
$302.00
Typical High
$812.83

Where North Carolina sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Carolina· 36th of 51

$537

AK $1,349NE $398

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.