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Full Gene Test For Inherited Tumor Risk

Missouri rates for HCPCS 81321

A laboratory test that reads the entire sequence of a single gene from a blood sample, looking for inherited changes linked to a higher risk of tumors. Reading the whole gene picks up changes anywhere along it, not only at the spots a shorter test checks.

Rates data updated October 2026.

How much does Full Gene Test For Inherited Tumor Risk cost?

$575

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $575 for this service. The price depends on where it is billed: about $550 from a physician practice, and about $1,047 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$550$389 to $871
FacilityA hospital or hospital-owned outpatient department$1,047$631 to $2,042

How much rates vary

Facilitymedian $1,047 · 10th to 90th $537 to $2,818Professionalmedian $550 · 10th to 90th $363 to $1,514
$500$1K$2K$5Kfacility $1,047professional $550

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$512.86
Median
$776.25
Typical High
$1,096.48
Aetna
Setting
Professional
Modifier
None
Typical Low
$436.52
Median
$512.86
Typical High
$691.83
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$602.56
Median
$602.56
Typical High
$2,754.23
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$389.05
Median
$549.54
Typical High
$1,071.52
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$416.87
Median
$602.56
Typical High
$1,148.15
Cigna
Setting
Facility
Modifier
None
Typical Low
$489.78
Median
$1,348.96
Typical High
$2,511.89
Cigna
Setting
Professional
Modifier
None
Typical Low
$275.42
Median
$660.69
Typical High
$870.96
Medica
Setting
Facility
Modifier
None
Typical Low
$537.03
Median
$1,047.13
Typical High
$2,818.38
Medica
Setting
Professional
Modifier
None
Typical Low
$302.00
Median
$602.56
Typical High
$3,019.95
United
Setting
Facility
Modifier
None
Typical Low
$537.03
Median
$537.03
Typical High
$537.03
United
Setting
Professional
Modifier
None
Typical Low
$251.19
Median
$363.08
Typical High
$812.83
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$257.04
Median
$257.04
Typical High
$346.74
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$102.33
Median
$102.33
Typical High
$138.04

Where Missouri sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 28th of 51

$575

AK $1,349NE $398

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.