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Full Gene Test For Inherited Tumor Risk

Missouri rates for HCPCS 81321

A laboratory test that reads the entire sequence of a single gene from a blood sample, looking for inherited changes linked to a higher risk of tumors. Reading the whole gene picks up changes anywhere along it, not only at the spots a shorter test checks.

Rates data updated July 2026.

How much does Full Gene Test For Inherited Tumor Risk cost?

$603

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $603 for this service. The price depends on where it is billed: about $550 from a physician practice, and about $776 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$550$457 to $692
FacilityA hospital or hospital-owned outpatient department$776$603 to $1,047

How much rates vary

Facilitymedian $776 · 10th to 90th $537 to $1,380Professionalmedian $550 · 10th to 90th $363 to $1,175
$500$1K$2Kfacility $776professional $550

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$575.44
Median
$1,000.00
Typical High
$1,380.38
Aetna
Setting
Professional
Modifier
Global
Typical Low
$457.09
Median
$524.81
Typical High
$1,202.26
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$602.56
Median
$602.56
Typical High
$2,089.30
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$389.05
Median
$549.54
Typical High
$1,071.52
BCBS
Setting
Professional
Modifier
Global
Typical Low
$416.87
Median
$602.56
Typical High
$676.08
Cigna
Setting
Facility
Modifier
Global
Typical Low
$416.87
Median
$1,174.90
Typical High
$2,511.89
Cigna
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$467.74
Typical High
$870.96
Medica
Setting
Facility
Modifier
Global
Typical Low
$512.86
Median
$724.44
Typical High
$2,818.38
Medica
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$363.08
Typical High
$3,019.95
United
Setting
Facility
Modifier
Global
Typical Low
$251.19
Median
$602.56
Typical High
$724.44
United
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$363.08
Typical High
$812.83

Where Missouri sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 20th of 51

$603

AK $1,349MD $447

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.