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Full Gene Test For Inherited Tumor Risk

Colorado rates for HCPCS 81321

A laboratory test that reads the entire sequence of a single gene from a blood sample, looking for inherited changes linked to a higher risk of tumors. Reading the whole gene picks up changes anywhere along it, not only at the spots a shorter test checks.

Rates data updated October 2026.

How much does Full Gene Test For Inherited Tumor Risk cost?

$794

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $794 for this service. The price depends on where it is billed: about $363 from a physician practice, and about $1,738 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$363$251 to $776
FacilityA hospital or hospital-owned outpatient department$1,738$1,122 to $2,089

How much rates vary

Facilitymedian $1,738 · 10th to 90th $457 to $2,754Professionalmedian $363 · 10th to 90th $251 to $1,259
$500$1K$2K$5Kfacility $1,738professional $363

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$602.56
Median
$1,258.93
Typical High
$2,754.23
Aetna
Setting
Professional
Modifier
None
Typical Low
$446.68
Median
$457.09
Typical High
$891.25
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$630.96
Median
$1,819.70
Typical High
$2,754.23
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$251.19
Median
$251.19
Typical High
$1,318.26
Cigna
Setting
Facility
Modifier
None
Typical Low
$354.81
Median
$724.44
Typical High
$1,905.46
Cigna
Setting
Professional
Modifier
None
Typical Low
$281.84
Median
$316.23
Typical High
$870.96
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$457.09
Median
$537.03
Typical High
$741.31
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$602.56
Median
$851.14
Typical High
$1,258.93
Select Health
Setting
Facility
Modifier
None
Typical Low
$602.56
Median
$1,122.02
Typical High
$1,258.93
Select Health
Setting
Professional
Modifier
None
Typical Low
$416.87
Median
$602.56
Typical High
$891.25
United
Setting
Facility
Modifier
None
Typical Low
$724.44
Median
$724.44
Typical High
$724.44
United
Setting
Professional
Modifier
None
Typical Low
$251.19
Median
$251.19
Typical High
$446.68
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$223.87
Median
$229.09
Typical High
$316.23
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$89.13
Median
$91.20
Typical High
$125.89

Where Colorado sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 5th of 51

$794

AK $1,349NE $398

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.