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PML/RARA Fusion Gene Test

Michigan rates for HCPCS 81316

Looks for an abnormal joining of the PML and RARA genes in a blood or bone marrow sample. This fusion is the defining feature of acute promyelocytic leukemia, a form of leukemia that responds to particular treatment, so the test is used to confirm the diagnosis quickly and to check afterwards whether any disease remains.

Rates data updated October 2026.

How much does PML/RARA Fusion Gene Test cost?

$200

Typical negotiated rate. In Michigan, October 2026.

Insurers have agreed to pay about $200 for this service. The price depends on where it is billed: about $200 from a physician practice, and about $195 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$200$155 to $263
FacilityA hospital or hospital-owned outpatient department$195$195 to $275

How much rates vary

Facilitymedian $195 · 10th to 90th $155 to $407Professionalmedian $200 · 10th to 90th $148 to $447
$10$20$50$100$200$500$1Kfacility $195professional $200

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$194.98
Typical High
$309.03
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$97.72
Median
$97.72
Typical High
$154.88
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$39.81
Median
$39.81
Typical High
$61.66
Aetna
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$204.17
Typical High
$245.47
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$97.72
Median
$102.33
Typical High
$123.03
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$39.81
Median
$40.74
Typical High
$48.98
BCBS Michigan
Setting
Facility
Modifier
None
Typical Low
$154.88
Median
$234.42
Typical High
$398.11
BCBS Michigan
Setting
Professional
Modifier
None
Typical Low
$147.91
Median
$154.88
Typical High
$154.88
Cigna
Setting
Professional
Modifier
None
Typical Low
$104.71
Median
$245.47
Typical High
$316.23
Health Alliance Plan
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$194.98
Typical High
$1,174.90
Health Alliance Plan
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$97.72
Median
$97.72
Typical High
$154.88
Health Alliance Plan
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$39.81
Median
$39.81
Typical High
$61.66
Health Alliance Plan
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$309.03
Typical High
$537.03
Health Alliance Plan
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$97.72
Median
$97.72
Typical High
$97.72
Health Alliance Plan
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$39.81
Median
$39.81
Typical High
$39.81
Priority Health
Setting
Professional
Modifier
None
Typical Low
$104.71
Median
$245.47
Typical High
$295.12
United
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$186.21
Typical High
$251.19
United
Setting
Professional
Modifier
None
Typical Low
$87.10
Median
$257.04
Typical High
$363.08

Where Michigan sits

The same service costs 3.4 times more in Texas than in Ohio. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 37th of 51

$200

TX $562OH $166

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.