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Cancer-Related Gene Mutation Test, Blood Or Tissue

South Carolina rates for HCPCS 81305

This service is a genetic laboratory test that looks for specific mutations in a gene commonly altered in certain blood or bone marrow cancers. Results can help confirm a diagnosis and guide treatment decisions. The test is typically run on a blood or bone marrow sample.

Rates data updated October 2026.

How much does Cancer-Related Gene Mutation Test, Blood Or Tissue cost?

$145

Typical negotiated rate. In South Carolina, October 2026.

Insurers have agreed to pay about $145 for this service. The price depends on where it is billed: about $145 from a physician practice, and about $363 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$145$87.10 to $174
FacilityA hospital or hospital-owned outpatient department$363$186 to $794

How much rates vary

Facilitymedian $363 · 10th to 90th $138 to $1,072Professionalmedian $145 · 10th to 90th $81 to $186
$100$200$500$1Kfacility $363professional $145

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$138.04
Typical High
$138.04
Aetna
Setting
Professional
Modifier
None
Typical Low
$138.04
Median
$138.04
Typical High
$141.25
BCBS South Carolina
Setting
Facility
Modifier
None
Typical Low
$933.25
Median
$933.25
Typical High
$977.24
BCBS South Carolina
Setting
Professional
Modifier
None
Typical Low
$81.28
Median
$144.54
Typical High
$173.78
Cigna
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$446.68
Typical High
$1,071.52
Cigna
Setting
Professional
Modifier
None
Typical Low
$79.43
Median
$83.18
Typical High
$213.80
Medcost
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$165.96
Typical High
$501.19
Medcost
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$245.47
United
Setting
Facility
Modifier
None
Typical Low
$158.49
Median
$158.49
Typical High
$208.93
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$104.71
Typical High
$173.78
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$69.18
Median
$69.18
Typical High
$70.79
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$27.54
Median
$27.54
Typical High
$28.18
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$87.10
Median
$87.10
Typical High
$141.25

Where South Carolina sits

The same service costs 3.8 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 40th of 51

$145

AK $398DE $105

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.