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Cancer-Related Gene Mutation Test, Blood Or Tissue

Missouri rates for HCPCS 81305

This service is a genetic laboratory test that looks for specific mutations in a gene commonly altered in certain blood or bone marrow cancers. Results can help confirm a diagnosis and guide treatment decisions. The test is typically run on a blood or bone marrow sample.

Rates data updated October 2026.

How much does Cancer-Related Gene Mutation Test, Blood Or Tissue cost?

$170

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $170 for this service. The price depends on where it is billed: about $151 from a physician practice, and about $302 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$151$105 to $282
FacilityA hospital or hospital-owned outpatient department$302$182 to $447

How much rates vary

Facilitymedian $302 · 10th to 90th $170 to $832Professionalmedian $151 · 10th to 90th $87 to $457
$100$200$500$1Kfacility $302professional $151

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$147.91
Median
$223.87
Typical High
$323.59
Aetna
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$151.36
Typical High
$186.21
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$812.83
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$104.71
Median
$165.96
Typical High
$331.13
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$245.47
Median
$269.15
Typical High
$478.63
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$173.78
Typical High
$331.13
Cigna
Setting
Facility
Modifier
None
Typical Low
$181.97
Median
$389.05
Typical High
$912.01
Cigna
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$138.04
Typical High
$229.09
Medica
Setting
Facility
Modifier
None
Typical Low
$158.49
Median
$302.00
Typical High
$831.76
Medica
Setting
Professional
Modifier
None
Typical Low
$87.10
Median
$181.97
Typical High
$870.96
United
Setting
Facility
Modifier
None
Typical Low
$158.49
Median
$158.49
Typical High
$158.49
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$104.71
Typical High
$234.42
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$74.13
Median
$75.86
Typical High
$100.00
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$29.51
Median
$30.20
Typical High
$40.74

Where Missouri sits

The same service costs 3.8 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 29th of 51

$170

AK $398DE $105

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.