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Cancer-Related Gene Mutation Test, Blood Or Tissue

Indiana rates for HCPCS 81305

This service is a genetic laboratory test that looks for specific mutations in a gene commonly altered in certain blood or bone marrow cancers. Results can help confirm a diagnosis and guide treatment decisions. The test is typically run on a blood or bone marrow sample.

Rates data updated October 2026.

How much does Cancer-Related Gene Mutation Test, Blood Or Tissue cost?

$141

Typical negotiated rate. In Indiana, October 2026.

Insurers have agreed to pay about $141 for this service. The price depends on where it is billed: about $105 from a physician practice, and about $174 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$105$70.79 to $162
FacilityA hospital or hospital-owned outpatient department$174$174 to $355

How much rates vary

Facilitymedian $174 · 10th to 90th $141 to $525Professionalmedian $105 · 10th to 90th $71 to $263
$100$200$500$1K$2Kfacility $174professional $105

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$144.54
Median
$245.47
Typical High
$645.65
Aetna
Setting
Professional
Modifier
None
Typical Low
$131.83
Median
$144.54
Typical High
$263.03
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$173.78
Typical High
$524.81
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$70.79
Median
$70.79
Typical High
$263.03
Cigna
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$501.19
Cigna
Setting
Professional
Modifier
None
Typical Low
$79.43
Median
$158.49
Typical High
$338.84
Physicians Health Plan of Northern Indiana
Setting
Facility
Modifier
None
Typical Low
$288.40
Median
$436.52
Typical High
$2,187.76
Physicians Health Plan of Northern Indiana
Setting
Professional
Modifier
None
Typical Low
$125.89
Median
$144.54
Typical High
$269.15
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$104.71
Typical High
$208.93
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$66.07
Median
$72.44
Typical High
$131.83
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$26.30
Median
$28.84
Typical High
$52.48

Where Indiana sits

The same service costs 3.8 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 41st of 51

$141

AK $398DE $105

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.