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Cancer-Related Gene Mutation Test, Blood Or Tissue

Illinois rates for HCPCS 81305

This service is a genetic laboratory test that looks for specific mutations in a gene commonly altered in certain blood or bone marrow cancers. Results can help confirm a diagnosis and guide treatment decisions. The test is typically run on a blood or bone marrow sample.

Rates data updated July 2026.

How much does Cancer-Related Gene Mutation Test, Blood Or Tissue cost?

$145

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $145 for this service. The price depends on where it is billed: about $135 from a physician practice, and about $275 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$135$105 to $151
FacilityA hospital or hospital-owned outpatient department$275$178 to $363

How much rates vary

Facilitymedian $275 · 10th to 90th $145 to $479Professionalmedian $135 · 10th to 90th $3 to $269
$5.0$20.0$100.0$500.0$2.0Kfacility $275professional $135

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$144.54
Median
$269.15
Typical High
$407.38
Aetna
Setting
Professional
Modifier
Global
Typical Low
$125.89
Median
$144.54
Typical High
$302.00
BCBS
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$281.84
Typical High
$2,290.87
BCBS
Setting
Professional
Modifier
Global
Typical Low
$3.47
Median
$120.23
Typical High
$134.90
Cigna
Setting
Facility
Modifier
Global
Typical Low
$323.59
Median
$407.38
Typical High
$812.83
Cigna
Setting
Professional
Modifier
Global
Typical Low
$79.43
Median
$213.80
Typical High
$295.12
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$194.98
Median
$309.03
Typical High
$501.19
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$229.09
Median
$229.09
Typical High
$229.09
United
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$354.81
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$104.71
Typical High
$177.83

Where Illinois sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Illinois $145 · 40th of 51
AK $398DE $117

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.