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Cancer-Related Gene Mutation Test, Blood Or Tissue

Iowa rates for HCPCS 81305

This service is a genetic laboratory test that looks for specific mutations in a gene commonly altered in certain blood or bone marrow cancers. Results can help confirm a diagnosis and guide treatment decisions. The test is typically run on a blood or bone marrow sample.

Rates data updated October 2026.

How much does Cancer-Related Gene Mutation Test, Blood Or Tissue cost?

$186

Typical negotiated rate. In Iowa, October 2026.

Insurers have agreed to pay about $186 for this service. The price depends on where it is billed: about $174 from a physician practice, and about $229 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$174$105 to $331
FacilityA hospital or hospital-owned outpatient department$229$174 to $389

How much rates vary

Facilitymedian $229 · 10th to 90th $174 to $490Professionalmedian $174 · 10th to 90th $105 to $692
$100$200$500facility $229professional $174

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$371.54
Typical High
$489.78
Aetna
Setting
Professional
Modifier
None
Typical Low
$117.49
Median
$138.04
Typical High
$208.93
Cigna
Setting
Professional
Modifier
None
Typical Low
$213.80
Median
$338.84
Typical High
$416.87
Hally Health
Setting
Professional
Modifier
None
Typical Low
$151.36
Median
$263.03
Typical High
$389.05
Medica
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$229.09
Typical High
$446.68
Medica
Setting
Professional
Modifier
None
Typical Low
$104.71
Median
$208.93
Typical High
$870.96
Midlands
Setting
Professional
Modifier
None
Typical Low
$213.80
Median
$213.80
Typical High
$234.42
Oscar Health
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$190.55
Typical High
$371.54
United
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$446.68
United
Setting
Professional
Modifier
None
Typical Low
$104.71
Median
$104.71
Typical High
$363.08
Wellmark
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$69.18
Median
$69.18
Typical High
$104.71
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$27.54
Median
$27.54
Typical High
$41.69

Where Iowa sits

The same service costs 3.8 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 17th of 51

$186

AK $398DE $105

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.