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Cancer-Related Gene Mutation Test, Blood Or Tissue

Colorado rates for HCPCS 81305

This service is a genetic laboratory test that looks for specific mutations in a gene commonly altered in certain blood or bone marrow cancers. Results can help confirm a diagnosis and guide treatment decisions. The test is typically run on a blood or bone marrow sample.

Rates data updated July 2026.

How much does Cancer-Related Gene Mutation Test, Blood Or Tissue cost?

$186

Typical negotiated rate. In Colorado, July 2026.

Insurers have agreed to pay about $186 for this service. The price depends on where it is billed: about $132 from a physician practice, and about $427 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$132$105 to $141
FacilityA hospital or hospital-owned outpatient department$427$234 to $724

How much rates vary

Facilitymedian $427 · 10th to 90th $135 to $891Professionalmedian $132 · 10th to 90th $74 to $186
$100$200$500$1Kfacility $427professional $132

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$109.65
Median
$380.19
Typical High
$831.76
Aetna
Setting
Professional
Modifier
Global
Typical Low
$109.65
Median
$131.83
Typical High
$186.21
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$218.78
Median
$524.81
Typical High
$891.25
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$74.13
Typical High
$173.78
Cigna
Setting
Facility
Modifier
Global
Typical Low
$102.33
Median
$114.82
Typical High
$457.09
Cigna
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$93.33
Typical High
$251.19
Denver HMP
Setting
Facility
Modifier
Global
Typical Low
$131.83
Median
$173.78
Typical High
$263.03
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$251.19
Typical High
$467.74
Select Health
Setting
Facility
Modifier
Global
Typical Low
$186.21
Median
$323.59
Typical High
$371.54
Select Health
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$173.78
Typical High
$263.03
United
Setting
Facility
Modifier
Global
Typical Low
$158.49
Median
$173.78
Typical High
$263.03
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$74.13
Typical High
$104.71

Where Colorado sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 12th of 51

$186

AK $398DE $117

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.