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Cancer-Related Gene Mutation Test, Blood Or Tissue

Colorado rates for HCPCS 81305

This service is a genetic laboratory test that looks for specific mutations in a gene commonly altered in certain blood or bone marrow cancers. Results can help confirm a diagnosis and guide treatment decisions. The test is typically run on a blood or bone marrow sample.

Rates data updated October 2026.

How much does Cancer-Related Gene Mutation Test, Blood Or Tissue cost?

$234

Typical negotiated rate. In Colorado, October 2026.

Insurers have agreed to pay about $234 for this service. The price depends on where it is billed: about $105 from a physician practice, and about $513 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$105$74.13 to $229
FacilityA hospital or hospital-owned outpatient department$513$331 to $603

How much rates vary

Facilitymedian $513 · 10th to 90th $135 to $794Professionalmedian $105 · 10th to 90th $74 to $363
$100$200$500$1Kfacility $513professional $105

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$177.83
Median
$371.54
Typical High
$812.83
Aetna
Setting
Professional
Modifier
None
Typical Low
$131.83
Median
$131.83
Typical High
$186.21
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$186.21
Median
$524.81
Typical High
$794.33
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$74.13
Typical High
$389.05
Cigna
Setting
Facility
Modifier
None
Typical Low
$102.33
Median
$213.80
Typical High
$549.54
Cigna
Setting
Professional
Modifier
None
Typical Low
$77.62
Median
$91.20
Typical High
$251.19
Denver HMP
Setting
Facility
Modifier
None
Typical Low
$131.83
Median
$158.49
Typical High
$218.78
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$251.19
Typical High
$446.68
Select Health
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$323.59
Typical High
$371.54
Select Health
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$173.78
Typical High
$263.03
United
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$74.13
Typical High
$128.82
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$66.07
Median
$66.07
Typical High
$93.33
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$26.30
Median
$26.92
Typical High
$37.15

Where Colorado sits

The same service costs 3.8 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Colorado· 5th of 51

$234

AK $398DE $105

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.