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MECP2 Full Gene Sequencing

Massachusetts rates for HCPCS 81302

A test that reads through the entire MECP2 gene looking for any change that could explain a child's symptoms. Changes in this gene cause Rett syndrome, a disorder of brain development seen mainly in girls, in which speech and hand skills are lost after a period of normal early growth. It is usually performed on a blood sample.

Rates data updated October 2026.

How much does MECP2 Full Gene Sequencing cost?

$550

Typical negotiated rate. In Massachusetts, October 2026.

Insurers have agreed to pay about $550 for this service. The price depends on where it is billed: about $525 from a physician practice, and about $891 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$525$316 to $1,318
FacilityA hospital or hospital-owned outpatient department$891$708 to $1,288

How much rates vary

Facilitymedian $891 · 10th to 90th $525 to $1,738Professionalmedian $525 · 10th to 90th $316 to $2,630
$100$200$500$1K$2K$5Kfacility $891professional $525

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$323.59
Median
$323.59
Typical High
$323.59
Aetna
Setting
Professional
Modifier
None
Typical Low
$323.59
Median
$323.59
Typical High
$323.59
AllWays Health Partners
Setting
Facility
Modifier
None
Typical Low
$575.44
Median
$891.25
Typical High
$1,737.80
AllWays Health Partners
Setting
Professional
Modifier
None
Typical Low
$316.23
Median
$1,000.00
Typical High
$2,630.27
BCBS Massachusetts
Setting
Facility
Modifier
None
Typical Low
$831.76
Median
$1,174.90
Typical High
$1,698.24
BCBS Massachusetts
Setting
Professional
Modifier
None
Typical Low
$138.04
Median
$138.04
Typical High
$138.04
Cigna
Setting
Facility
Modifier
None
Typical Low
$288.40
Median
$489.78
Typical High
$1,023.29
Cigna
Setting
Professional
Modifier
None
Typical Low
$316.23
Median
$562.34
Typical High
$2,041.74
Fallon Health
Setting
Facility
Modifier
None
Typical Low
$83.18
Median
$891.25
Typical High
$5,888.44
Fallon Health
Setting
Professional
Modifier
None
Typical Low
$758.58
Median
$758.58
Typical High
$891.25
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$223.87
Median
$524.81
Typical High
$1,174.90
Mass General Brigham
Setting
Facility
Modifier
None
Typical Low
$575.44
Median
$891.25
Typical High
$1,737.80
Mass General Brigham
Setting
Professional
Modifier
None
Typical Low
$316.23
Median
$1,000.00
Typical High
$2,630.27
United
Setting
Facility
Modifier
None
Typical Low
$478.63
Median
$524.81
Typical High
$630.96
United
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$316.23
Typical High
$1,000.00
Well Sense
Setting
Facility
Modifier
None
Typical Low
$467.74
Median
$645.65
Typical High
$954.99
Well Sense
Setting
Professional
Modifier
None
Typical Low
$2,511.89
Median
$2,511.89
Typical High
$3,019.95
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$162.18
Median
$162.18
Typical High
$162.18
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$64.57
Median
$64.57
Typical High
$64.57
Fallon Health
Setting
Facility
Modifier
QW · Waived lab test
Typical Low
$524.81
Median
$691.83
Typical High
$812.83

Where Massachusetts sits

The same service costs 4.5 times more in Texas than in New Mexico. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 17th of 51

$550

TX $1,413NM $316

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.